{"id":"W4293214379","doi":"10.1021/acsinfecdis.2c00313","title":"A54145 Factor D Is Not Less Susceptible to Inhibition by Lung Surfactant than Daptomycin","year":2022,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Waterloo Institute for Nanotechnology, University of Waterloo; Natural Sciences and Engineering Research Council of Canada","keywords":"Daptomycin; Pulmonary surfactant; Lung; Medicine; Internal medicine; Microbiology; Chemistry; Biology; Bacteria; Biochemistry; Vancomycin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001202796,0.000197864,0.0002625278,0.0001536972,0.0000959129,0.0003448705,0.0001488033,0.0003563027,0.001272854],"category_scores_gemma":[0.0003157661,0.00009880257,0.0002474166,0.0001179627,0.0001830813,0.0001396896,0.0001386123,0.0003381804,0.0003371171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003264317,"about_ca_system_score_gemma":0.0002818841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001841428,"about_ca_topic_score_gemma":0.0009739199,"domain_scores_codex":[0.9997107,0.00003929114,0.00003753107,0.00005999273,0.00008835988,0.00006414526],"domain_scores_gemma":[0.999799,0.00004204558,0.00005400283,0.00002403708,0.00003087279,0.000050096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001621305,0.00001806448,0.0003107652,0.00002411994,0.000006752031,0.00003952115,0.000006417887,0.00003894451,0.998229,0.00004291536,0.00003942053,0.001082038],"study_design_scores_gemma":[0.00004271352,0.00122488,0.007116982,0.00000797142,0.00001329863,0.0005056252,0.00003754458,0.0007450535,0.9866452,0.00002702564,0.003625172,0.000008544283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962988,0.001473536,0.0005403107,0.0000586563,0.00002174551,0.00001593128,0.0001800557,0.00002702136,0.001384019],"genre_scores_gemma":[0.9976304,0.0002909208,0.0005234586,0.0000540522,0.000005826196,0.000008964246,0.0004666597,0.000007487765,0.001012282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001841428,"threshold_uncertainty_score":0.004258156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0151288750290362,"score_gpt":0.2678871775944136,"score_spread":0.2527583025653773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}