{"id":"W4293214379","doi":"10.1021/acsinfecdis.2c00313","title":"A54145 Factor D Is Not Less Susceptible to Inhibition by Lung Surfactant than Daptomycin","year":2022,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Waterloo Institute for Nanotechnology, University of Waterloo; Natural Sciences and Engineering Research Council of Canada","keywords":"Daptomycin; Pulmonary surfactant; Lung; Medicine; Internal medicine; Microbiology; Chemistry; Biology; Bacteria; Biochemistry; Vancomycin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008473031,0.0002038204,0.0002602568,0.0002199203,0.000485781,0.00004627505,0.0000701023,0.00005649575,0.002705339],"category_scores_gemma":[0.00005588996,0.000196155,0.0001431138,0.0004058135,0.00004372023,0.0001300288,0.0001285273,0.0002350915,0.000136166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003553177,"about_ca_system_score_gemma":0.0001723995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001431186,"about_ca_topic_score_gemma":0.00001692991,"domain_scores_codex":[0.9984342,0.0001084672,0.0002669451,0.0003672016,0.0005210534,0.0003020718],"domain_scores_gemma":[0.9991035,0.00006328416,0.00009188672,0.0003046244,0.0001253062,0.0003114171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004934843,0.001517358,0.629758,0.0002034167,0.0001999699,0.0001554933,0.00134009,0.0003281115,0.1433958,0.0001862414,0.2196687,0.002753291],"study_design_scores_gemma":[0.0160697,0.005743421,0.3140388,0.0003728998,0.001321945,0.0003713889,0.006842962,0.001118737,0.4355916,0.0001202239,0.2152044,0.003203828],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994778,0.0002136184,0.00006449485,0.0008486391,0.00042839,0.0005855832,0.0008563839,0.0002814683,0.001943379],"genre_scores_gemma":[0.9901686,0.00002727229,0.000004187146,0.007502363,0.0001614736,0.0001047922,0.0002287947,0.00004263583,0.001759832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3157192,"threshold_uncertainty_score":0.9982063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0151288750290362,"score_gpt":0.2678871775944136,"score_spread":0.2527583025653773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}