{"id":"W4293242071","doi":"10.1007/s13555-022-00790-2","title":"Clinical Efficacy and Safety of Psoriasis Treatments in Patients with Concomitant Metabolic Syndrome: A Narrative Review","year":2022,"lang":"en","type":"review","venue":"Dermatology and Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"LEO Pharma; Bausch Health; Castle Biosciences; Galderma; Bristol-Myers Squibb; Eli Lilly and Company; Ortho Dermatologics; Sanofi Genzyme; Incyte; Regeneron Pharmaceuticals; Helsinn; Celgene; Biogen; Sanofi; Amgen; Helsinn Therapeutics; Meiji Seika Pharma; Pfizer","keywords":"Medicine; Psoriasis; Concomitant; Metabolic syndrome; Internal medicine; Exacerbation; Comorbidity; Observational study; Dermatology; Obesity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003086841,0.0005380191,0.003967004,0.0002020978,0.0001707004,0.000003941888,0.000187553,0.0005130129,0.0003205712],"category_scores_gemma":[0.00003922259,0.0003472211,0.0002596147,0.0002882919,0.0004009776,0.00005287298,0.00007647287,0.000412311,0.00001218426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002272085,"about_ca_system_score_gemma":0.0001364023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001245048,"about_ca_topic_score_gemma":0.000004631423,"domain_scores_codex":[0.9956705,0.002302505,0.001086659,0.0005844896,0.00004904061,0.0003068311],"domain_scores_gemma":[0.997907,0.0009953113,0.0006655677,0.0003623716,0.00003048165,0.00003929908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007780989,0.0007606987,0.01841796,0.001591246,0.005392236,0.00007140284,0.0002747634,5.738189e-9,7.67773e-8,0.0001066515,0.00008531637,0.9725215],"study_design_scores_gemma":[0.01397611,0.000877158,0.03237196,0.004286306,0.002984599,0.0007704711,0.00003240947,1.296843e-8,0.000001748409,0.00001400479,0.9442946,0.000390627],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04886608,0.9487095,2.677886e-7,0.0000295386,0.0002912821,0.001809504,0.0002089394,0.00001778802,0.0000670937],"genre_scores_gemma":[0.002270003,0.9964263,0.00001966839,0.0001105485,0.000005177181,0.0002571256,0.0008188768,0.00003229049,0.00005996173],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9721309,"threshold_uncertainty_score":0.999898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03552805040761128,"score_gpt":0.3204511661888236,"score_spread":0.2849231157812123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}