{"id":"W4293246599","doi":"10.1101/2022.05.10.491389","title":"A Commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA)","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Pleckstrin homology domain; Immunocytochemistry; Immunoprecipitation; Mitosis; Cell biology; Guanine nucleotide exchange factor; Biology; Molecular biology; Blot; Cytoskeleton; Spindle apparatus; Chemistry; Antibody; Cell; Biochemistry; Cell division; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007316634,0.001379459,0.0005349388,0.001701383,0.0008094897,0.0005682622,0.0009180791,0.001095494,0.02886859],"category_scores_gemma":[0.0004706954,0.0006281429,0.0005481942,0.0005698911,0.0005184554,0.0004434374,0.0006371284,0.001328699,0.008856462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006125602,"about_ca_system_score_gemma":0.0004015627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005973832,"about_ca_topic_score_gemma":0.001268613,"domain_scores_codex":[0.9992309,0.00009267117,0.00005158562,0.0002702404,0.000195772,0.0001588528],"domain_scores_gemma":[0.9995697,0.0001313774,0.00003977958,0.00008740362,0.0001036156,0.00006803041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002500227,0.0001044663,0.0006781986,0.0001917042,0.00003828036,0.0002695278,0.00004349971,0.00007741959,0.988373,0.001461827,0.002275359,0.006236658],"study_design_scores_gemma":[0.00008180702,0.000185542,0.007480777,0.00004611033,0.00007260976,0.002885459,0.00005445605,0.001894459,0.9395803,0.0005779283,0.04712696,0.00001365936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7061445,0.009780245,0.183947,0.002320516,0.001500201,0.0006257151,0.004797339,0.006324424,0.08456007],"genre_scores_gemma":[0.574764,0.004976776,0.2079197,0.000893255,0.0005255569,0.001177401,0.03060719,0.001960241,0.1771759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02886859,"threshold_uncertainty_score":0.09657502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008882220611154675,"score_gpt":0.238199155070069,"score_spread":0.2293169344589144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}