{"id":"W4293282442","doi":"10.1016/s2666-7568(22)00169-6","title":"Integrated Geriatric Assessment and Treatment Effectiveness (INTEGERATE) in older people with cancer starting systemic anticancer treatment in Australia: a multicentre, open-label, randomised controlled trial","year":2022,"lang":"en","type":"article","venue":"The Lancet Healthy Longevity","topic":"Frailty in Older Adults","field":"Medicine","cited_by":211,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Medical Research Council; Monash University; Eastern Health","keywords":"Medicine; Open label; Cancer; Randomized controlled trial; Intensive care medicine; Internal medicine; Oncology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002315429,0.0004500702,0.00245564,0.0001772702,0.0002622359,0.00007963688,0.0002197548,0.00007946648,0.0001695199],"category_scores_gemma":[0.000102628,0.000256009,0.00007079308,0.0007554704,0.00007068688,0.0001226335,0.0001077161,0.0005508902,0.000002178474],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005744074,"about_ca_system_score_gemma":0.001283823,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.05071273,"about_ca_topic_score_gemma":0.03703801,"domain_scores_codex":[0.9945843,0.002728091,0.0008163834,0.0006909334,0.0004065298,0.0007737653],"domain_scores_gemma":[0.9973637,0.001426329,0.0003952179,0.0005407602,0.00009295822,0.0001809754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7993401,0.003775429,0.1854311,0.0003778515,0.0004033029,0.0001746499,0.00431545,0.0008751032,0.0003122894,0.00001410714,0.00005366948,0.004926984],"study_design_scores_gemma":[0.8339334,0.005473535,0.1531283,0.0005033503,0.0003416191,0.00004090908,0.0009503149,0.005293943,0.00005524402,0.000007529095,0.00004211583,0.0002298243],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9635847,0.001245509,0.00002195912,0.003453695,0.0003817246,0.03111176,0.00009028168,0.00004770873,0.00006268004],"genre_scores_gemma":[0.9787372,0.001117146,0.0001523437,0.0002855744,0.0001780872,0.01917687,0.00004917949,0.00004027653,0.0002633401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03459331,"threshold_uncertainty_score":0.9999892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06328126089741115,"score_gpt":0.3923756849195225,"score_spread":0.3290944240221113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}