{"id":"W4293354733","doi":"10.1002/pi.6450","title":"Tethered drug release from model contact lenses","year":2022,"lang":"en","type":"article","venue":"Polymer International","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Contact lens; Drug delivery; Silicone; Materials science; Drug; Bioavailability; Methacrylate; Succinic anhydride; Lactide; Ethylene glycol; Lens (geology); Chemistry; Polymer chemistry; Nanotechnology; Organic chemistry; Polymer; Polymerization; Composite material; Pharmacology; Ophthalmology; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001723435,0.0003293969,0.0002007514,0.0002101232,0.0001274349,0.0003071559,0.0002042111,0.0002329932,0.001436786],"category_scores_gemma":[0.0002533918,0.0001116059,0.0002216658,0.0001796516,0.0001664428,0.0003119227,0.0001372509,0.0003669957,0.0002649755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004016946,"about_ca_system_score_gemma":0.0002465568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001192943,"about_ca_topic_score_gemma":0.001248073,"domain_scores_codex":[0.9998549,0.0000163871,0.00001274017,0.00003421101,0.00005616904,0.00002561238],"domain_scores_gemma":[0.9998233,0.0000553591,0.00005126901,0.00001989674,0.00002762081,0.00002256709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007008272,0.00002051313,0.00004785124,0.00003800863,0.000004033386,0.00003411743,0.00001817037,0.000112833,0.9983857,0.00003191981,0.00002151643,0.001215203],"study_design_scores_gemma":[0.000006994207,0.0003136331,0.0004889657,0.000002880629,0.000005258781,0.00002521417,0.000007920224,0.0004532369,0.9980791,0.000007783962,0.0006057686,0.000003243947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938881,0.001158182,0.003428294,0.00002996221,0.00002944016,0.00004114311,0.0002253864,0.00008211192,0.001117451],"genre_scores_gemma":[0.9928837,0.0006678092,0.002582075,0.00001788028,0.000008175852,0.00002929564,0.000228447,0.00003140108,0.00355132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436786,"threshold_uncertainty_score":0.004806578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01656882713464121,"score_gpt":0.2617891159744302,"score_spread":0.245220288839789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}