{"id":"W4293440049","doi":"10.23880/izab-16000371","title":"“Proof of Concept” Rabbit Experiments Demonstrating GHR106 (hIgG4) as GnRH Antagonist","year":2022,"lang":"en","type":"article","venue":"International Journal of Zoology and Animal Biology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Biotech (Canada); University of British Columbia","funders":"","keywords":"Hormone; Antagonist; Testosterone (patch); Internal medicine; Endocrinology; Antibody; Subcutaneous injection; Monoclonal antibody; Receptor; Biology; Chemistry; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003762235,0.0001045536,0.0003841153,0.0001715462,0.00007083831,0.000005011199,0.0001931223,0.00006775362,0.0004791736],"category_scores_gemma":[0.0002659885,0.0000890742,0.00010649,0.00004425569,0.0003738037,0.00006235456,0.0001408179,0.0003306453,0.000001502926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005362205,"about_ca_system_score_gemma":0.0001546062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002561891,"about_ca_topic_score_gemma":0.000001393956,"domain_scores_codex":[0.9988396,0.0001468901,0.0005085662,0.0001819911,0.0001847723,0.0001381643],"domain_scores_gemma":[0.9989104,0.0001373903,0.0004989187,0.00007453284,0.0003221001,0.00005663526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003500138,0.0003329356,0.1560877,0.000005741334,0.0007240456,0.0004075475,0.0004328747,0.00001089797,0.8126436,0.005418218,0.0001202463,0.02031605],"study_design_scores_gemma":[0.01992847,0.03288073,0.3161905,0.0001172482,0.0004701898,0.06105218,0.006290911,0.0003041887,0.5334198,0.007737829,0.02101323,0.0005946954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892128,0.00449407,0.0002015784,0.004450549,0.0005957449,0.00009068772,0.00002078174,0.000005032639,0.0009287512],"genre_scores_gemma":[0.998367,0.00005600818,0.000645645,0.0004304989,0.0003528636,0.000004377094,0.0000116782,0.000007264,0.0001246991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2792237,"threshold_uncertainty_score":0.5246614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01906247240779818,"score_gpt":0.3151958483326628,"score_spread":0.2961333759248646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}