{"id":"W4293440049","doi":"10.23880/izab-16000371","title":"“Proof of Concept” Rabbit Experiments Demonstrating GHR106 (hIgG4) as GnRH Antagonist","year":2022,"lang":"en","type":"article","venue":"International Journal of Zoology and Animal Biology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Biotech (Canada); University of British Columbia","funders":"","keywords":"Hormone; Antagonist; Testosterone (patch); Internal medicine; Endocrinology; Antibody; Subcutaneous injection; Monoclonal antibody; Receptor; Biology; Chemistry; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001517305,0.0008426243,0.0006523078,0.000293193,0.0002502113,0.0005146862,0.001066393,0.00130823,0.003717697],"category_scores_gemma":[0.0007177541,0.000442763,0.0008757009,0.0002228866,0.0004519835,0.0005506961,0.0002990507,0.001379389,0.002150538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003369557,"about_ca_system_score_gemma":0.0003960806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004353086,"about_ca_topic_score_gemma":0.0004152131,"domain_scores_codex":[0.9992411,0.0001523146,0.0001119115,0.0001406646,0.0002221128,0.0001318754],"domain_scores_gemma":[0.9994137,0.00006677508,0.000181991,0.0001288221,0.0001149986,0.00009365013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004349063,0.0002041272,0.0001417216,0.0001205666,0.00002530115,0.0001880216,0.00002709863,0.00008412848,0.9954366,0.0005070216,0.0004315492,0.00239897],"study_design_scores_gemma":[0.0003889759,0.006573278,0.001433921,0.00001898106,0.0001032931,0.001847078,0.00003302614,0.0009242213,0.9726848,0.0001254364,0.01585123,0.00001571688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8690036,0.004911474,0.1041766,0.001481582,0.001570116,0.003371059,0.002481069,0.001224911,0.0117795],"genre_scores_gemma":[0.9067485,0.004129686,0.06452851,0.0007701439,0.0002132433,0.002202346,0.004233055,0.000192117,0.01698234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003717697,"threshold_uncertainty_score":0.01243693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01906247240779818,"score_gpt":0.3151958483326628,"score_spread":0.2961333759248646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}