{"id":"W4293479337","doi":"10.1016/j.mib.2022.102198","title":"Antifungal discovery","year":2022,"lang":"en","type":"review","venue":"Current Opinion in Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs; Canadian Institute for Advanced Research","keywords":"Antifungal; Biology; Drug discovery; Antifungal drug; Identification (biology); Antifungal drugs; Computational biology; Human health; Biotechnology; Bioinformatics; Microbiology; Medicine; Environmental health; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000413768,0.0004183192,0.002049137,0.0003412909,0.00007210417,0.0000168603,0.0002715515,0.0003206048,0.001283946],"category_scores_gemma":[0.0001543767,0.0003333814,0.0006868538,0.0004301024,0.0001858321,0.0000616715,0.000264056,0.00137394,0.0001641893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004180353,"about_ca_system_score_gemma":0.0007163724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005129551,"about_ca_topic_score_gemma":0.000002436514,"domain_scores_codex":[0.9973832,0.0004065305,0.0008665349,0.0007988937,0.00008755516,0.0004572525],"domain_scores_gemma":[0.9987999,0.0002488671,0.0002673966,0.0005896488,0.00002170894,0.00007247116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006889935,0.0004533234,0.001482992,0.04782813,0.00007518948,0.00001131583,0.00002561856,6.79817e-8,0.00002314172,0.000281651,0.01940916,0.9303405],"study_design_scores_gemma":[0.0003446407,0.0001166746,0.0001302154,0.009457854,0.0001169547,0.0001611141,0.00001784816,2.289418e-7,4.7555e-7,0.00001224217,0.9893586,0.0002831377],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004292581,0.9891695,0.00002184107,0.00001813146,0.009102247,0.0009385468,0.0003986065,0.00003576704,0.0002724359],"genre_scores_gemma":[0.00001587169,0.9937828,0.00002307124,0.00001809064,0.0005031014,0.000119285,0.005019836,0.00004112219,0.0004768355],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9699494,"threshold_uncertainty_score":0.9999118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1472185924700774,"score_gpt":0.4255639808690065,"score_spread":0.2783453883989291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}