{"id":"W4293498722","doi":"10.3389/fimmu.2022.946905","title":"“Just one word, plastic!”: Controversies and caveats in innate lymphoid cell plasticity","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; AllerGen","keywords":"Innate lymphoid cell; Biology; Plasticity; Transcription factor; Innate immune system; Neuroscience; Immune system; Cell biology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02031451,0.0008216211,0.002149587,0.002634888,0.002328059,0.006922148,0.003990002,0.007612485,0.003520572],"category_scores_gemma":[0.037103,0.0005827761,0.001329405,0.002678743,0.02434095,0.02118885,0.004672222,0.02133586,0.002541006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002432961,"about_ca_system_score_gemma":0.003676285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002239698,"about_ca_topic_score_gemma":0.00218247,"domain_scores_codex":[0.9919555,0.003572436,0.0009005197,0.001279503,0.001897046,0.0003950249],"domain_scores_gemma":[0.9450213,0.04653615,0.001539761,0.00179306,0.004086616,0.001023224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002593054,0.00007274532,0.0009910548,0.00772891,0.0002818049,0.001125088,0.004400792,0.0005664468,0.001776828,0.2095365,0.3889821,0.3842785],"study_design_scores_gemma":[0.00002046474,0.00009088004,0.0006820383,0.003799782,0.00007597166,0.002034912,0.002054698,0.0002512981,0.0007804346,0.1459849,0.8441293,0.00009528889],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009140994,0.6784802,0.003422377,0.2904646,0.02343535,0.00001019603,0.00008389897,0.00007270072,0.003116457],"genre_scores_gemma":[0.02163207,0.5790744,0.003275517,0.3082049,0.08433113,0.0000785446,0.0001320513,0.000226013,0.003045351],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02031451,"threshold_uncertainty_score":0.1074347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02359383389887275,"score_gpt":0.2341114637747818,"score_spread":0.2105176298759091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}