{"id":"W4293554382","doi":"10.1186/s13063-022-06671-5","title":"Control of Line Complications with KiteLock (CLiCK) in the critical care unit: study protocol for a multi-center, cluster-randomized, double-blinded, crossover trial investigating the effect of a novel locking fluid on central line complications in the critical care population","year":2022,"lang":"en","type":"article","venue":"Trials","topic":"Central Venous Catheters and Hemodialysis","field":"Health Professions","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fraser Health; Centre for Advancing Health Outcomes; University of British Columbia; University of Saskatchewan; Simon Fraser University","funders":"Mitacs","keywords":"Medicine; Catheter; Population; Intensive care unit; Crossover study; Bacteremia; Randomized controlled trial; Central line; Intensive care medicine; Occlusion; Central venous catheter; Intensive care; Emergency medicine; Surgery; Anesthesia; Antibiotics; Placebo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009865411,0.00370813,0.007761847,0.0009643541,0.001625389,0.002260049,0.002047604,0.005051095,0.02104292],"category_scores_gemma":[0.008670566,0.001320626,0.003070713,0.001067713,0.002211766,0.002009809,0.00104502,0.003783606,0.003458095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002039837,"about_ca_system_score_gemma":0.007326772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009376889,"about_ca_topic_score_gemma":0.001954806,"domain_scores_codex":[0.9944651,0.002663628,0.000673752,0.0009070837,0.0004545556,0.0008359684],"domain_scores_gemma":[0.9953625,0.0009679176,0.001181518,0.0005588428,0.0008293689,0.001099858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9697887,0.01289115,0.0003871109,0.002726393,0.0008372028,0.00007209461,0.00009932295,0.0004378395,0.001675351,0.0005036691,0.002054988,0.00852613],"study_design_scores_gemma":[0.9554186,0.03879884,0.001021612,0.0003143032,0.0003772362,0.00001955425,0.00002683822,0.0004315245,0.0003362887,0.0003650111,0.002858691,0.00003148262],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.05194893,0.001143699,0.00355244,0.0007103415,0.0009210628,0.9377946,0.001878628,0.0002156745,0.001834717],"genre_scores_gemma":[0.03985186,0.0005031117,0.004965339,0.0006389164,0.0001768488,0.9524037,0.0004402362,0.00001517295,0.00100483],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02104292,"threshold_uncertainty_score":0.07039553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.370516456516884,"score_gpt":0.545480592306324,"score_spread":0.1749641357894399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}