{"id":"W4293554382","doi":"10.1186/s13063-022-06671-5","title":"Control of Line Complications with KiteLock (CLiCK) in the critical care unit: study protocol for a multi-center, cluster-randomized, double-blinded, crossover trial investigating the effect of a novel locking fluid on central line complications in the critical care population","year":2022,"lang":"en","type":"article","venue":"Trials","topic":"Central Venous Catheters and Hemodialysis","field":"Health Professions","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fraser Health; Centre for Advancing Health Outcomes; University of British Columbia; University of Saskatchewan; Simon Fraser University","funders":"Mitacs","keywords":"Medicine; Catheter; Population; Intensive care unit; Crossover study; Bacteremia; Randomized controlled trial; Central line; Intensive care medicine; Occlusion; Central venous catheter; Intensive care; Emergency medicine; Surgery; Anesthesia; Antibiotics; Placebo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.008604582,0.0002945688,0.001447899,0.0001916105,0.001492114,0.00005256857,0.0006289404,0.0001217531,0.00002014756],"category_scores_gemma":[0.005702723,0.0001482878,0.000395911,0.0006245758,0.0002862944,0.00006809792,0.0001101718,0.0008684092,6.556973e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002045278,"about_ca_system_score_gemma":0.0002387399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002060585,"about_ca_topic_score_gemma":0.002301186,"domain_scores_codex":[0.9863147,0.009658069,0.002351927,0.0004273435,0.0006797241,0.0005683018],"domain_scores_gemma":[0.969096,0.02890033,0.0007729975,0.0007502203,0.0004047951,0.00007565015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8563292,0.007825382,0.03186067,0.001173013,0.000163989,0.000001656756,0.08435725,0.009269074,0.0001315536,0.008382318,0.00004465797,0.0004612088],"study_design_scores_gemma":[0.9500076,0.003542553,0.005366961,0.0003649964,0.000572874,0.000002456283,0.02360831,0.01603081,0.00002921007,0.00008816284,0.0001955933,0.0001904336],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5365725,0.00004023273,0.004697849,0.004391833,0.0001740706,0.4531688,0.000890507,0.00002614162,0.000038046],"genre_scores_gemma":[0.6916443,3.094212e-7,0.0002461492,0.0005015112,0.000180861,0.3072604,0.0001419533,0.00002334735,0.000001255099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1550717,"threshold_uncertainty_score":0.9998078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.370516456516884,"score_gpt":0.545480592306324,"score_spread":0.1749641357894399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}