{"id":"W4293576969","doi":"10.1038/s41598-022-19040-8","title":"Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Grain Farmers of Ontario","keywords":"Detoxification (alternative medicine); Mycotoxin; Aldo-keto reductase; Function (biology); Reductase; Biology; Chemistry; Biochemistry; Enzyme; Botany; Medicine; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002581696,0.0005140596,0.0003406527,0.0001916737,0.0001428263,0.0002991922,0.0004255869,0.0003261763,0.0006463745],"category_scores_gemma":[0.0002018221,0.0001639381,0.0005726151,0.0003324109,0.0001771477,0.0001674701,0.0001641753,0.0003567597,0.0004261665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003170986,"about_ca_system_score_gemma":0.0002125324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001565977,"about_ca_topic_score_gemma":0.0009070482,"domain_scores_codex":[0.9998664,0.00002428734,0.00001360366,0.00002977212,0.00004311919,0.00002278708],"domain_scores_gemma":[0.9998727,0.00001295001,0.00003844579,0.000008165622,0.00003203694,0.0000356655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002566017,0.0001182709,0.001377977,0.00005329111,0.00001865736,0.0001578628,0.00003605128,0.0005020924,0.9960244,0.00007814842,0.00005574628,0.001320898],"study_design_scores_gemma":[0.0001141041,0.000916536,0.03668835,0.00001683975,0.0001230296,0.001397862,0.0001709596,0.009943593,0.943641,0.0001325281,0.006828915,0.00002622916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960259,0.0009602049,0.001600489,0.00008802857,0.00001614419,0.00002577468,0.0007557118,0.00002435348,0.0005033876],"genre_scores_gemma":[0.9899555,0.0005804241,0.00274978,0.00004528268,0.000008272439,0.00001098165,0.005202824,0.00001539916,0.001431465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001565977,"threshold_uncertainty_score":0.003113747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007526037504821589,"score_gpt":0.2184835306582686,"score_spread":0.210957493153447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}