{"id":"W4293685692","doi":"10.1016/s2665-9913(22)00185-0","title":"Effects of ixekizumab treatment on structural changes in the sacroiliac joint: MRI assessments at 16 weeks in patients with non-radiographic axial spondyloarthritis","year":2022,"lang":"en","type":"article","venue":"The Lancet Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Eli Lilly and Company","keywords":"Ixekizumab; Axial spondyloarthritis; Medicine; Sacroiliac joint; Radiography; Radiology; Magnetic resonance imaging; Nuclear medicine; Sacroiliitis; Internal medicine; Arthritis; Secukinumab; Psoriatic arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008228167,0.0004366023,0.0009969567,0.0001930861,0.0001850138,0.0003829963,0.0002209528,0.0006130648,0.001293062],"category_scores_gemma":[0.001579122,0.0002070693,0.0006085424,0.0001866184,0.0002465686,0.0004391747,0.0002099542,0.000866208,0.0002102819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003136057,"about_ca_system_score_gemma":0.0002836026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001210494,"about_ca_topic_score_gemma":0.002622845,"domain_scores_codex":[0.9996631,0.0001243171,0.00003493546,0.00005592572,0.00003561428,0.00008605699],"domain_scores_gemma":[0.9992895,0.0001697535,0.0002391888,0.00003764833,0.00006148076,0.0002023784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5851853,0.009563382,0.1992702,0.001291868,0.002329759,0.0009358392,0.0007508625,0.001728933,0.03755641,0.00005982055,0.001483985,0.1598436],"study_design_scores_gemma":[0.01390096,0.1078683,0.8727555,0.00008859312,0.0008207891,0.0004771947,0.0002842603,0.0005637493,0.00207834,0.00006681521,0.001043914,0.0000516363],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997061,0.002129887,0.00002800952,0.0001265226,0.00003442022,0.00002362362,0.0001040922,0.000005469612,0.0004869271],"genre_scores_gemma":[0.9988714,0.0004338965,0.00009605702,0.00006306732,0.000038337,0.00002162659,0.00011336,0.000001472793,0.0003606231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001293062,"threshold_uncertainty_score":0.004351497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096314380570307,"score_gpt":0.2540592955355598,"score_spread":0.2430961517298568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}