{"id":"W4293694671","doi":"10.1155/2022/3913439","title":"Clinical Considerations in the Selection of Preexposure Prophylaxis for HIV Prevention in Canada","year":2022,"lang":"en","type":"review","venue":"Canadian Journal of Infectious Diseases and Medical Microbiology","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto; Wellesley Institute; Clinique Paro Excellence; Maple Leaf Medical Clinic","funders":"Gilead Sciences","keywords":"Pre-exposure prophylaxis; Emtricitabine; Medicine; Tenofovir alafenamide; Men who have sex with men; Human immunodeficiency virus (HIV); Clinical trial; Family medicine; Public health; Antiretroviral therapy; Viral load; Internal medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007964847,0.0003204543,0.0009338412,0.002018765,0.00604138,0.006374005,0.00269313,0.002595837,0.007727559],"category_scores_gemma":[0.04390102,0.000389571,0.0009695058,0.003768517,0.002295017,0.002181083,0.002298605,0.004099174,0.0006147871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.04395222,"about_ca_system_score_gemma":0.1741247,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.933987,"about_ca_topic_score_gemma":0.977647,"domain_scores_codex":[0.9876345,0.003301005,0.001418958,0.0007562272,0.005120031,0.001769213],"domain_scores_gemma":[0.9688535,0.007560863,0.001925143,0.0003768296,0.01519053,0.006093172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00037158,0.0002552028,0.1010319,0.004261089,0.0002466079,0.003638407,0.006018987,0.0007439816,0.0005708811,0.01293162,0.3579602,0.5119696],"study_design_scores_gemma":[0.0003848275,0.000356719,0.1829334,0.02281832,0.0006574403,0.006267266,0.01530447,0.001282384,0.000819211,0.01146118,0.7573117,0.0004030333],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.03342352,0.2461396,0.002919425,0.5917248,0.004597744,0.0008807206,0.001985358,0.0001485179,0.1181804],"genre_scores_gemma":[0.4411413,0.280353,0.02071898,0.2329416,0.004229072,0.0007659736,0.00206503,0.000260352,0.0175245],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.06601298,"threshold_uncertainty_score":0.3188972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03358474256279313,"score_gpt":0.3577876124920482,"score_spread":0.324202869929255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}