{"id":"W4293719479","doi":"10.3748/wjg.v28.i33.4823","title":"Effectiveness, safety, and drug sustainability of biologics in elderly patients with inflammatory bowel disease: A retrospective study","year":2022,"lang":"en","type":"article","venue":"World Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University; McGill University Health Centre","funders":"","keywords":"Medicine; Infliximab; Ustekinumab; Inflammatory bowel disease; Ulcerative colitis; Internal medicine; Adverse effect; Adalimumab; Vedolizumab; Crohn's disease; Population; Maintenance therapy; Retrospective cohort study; Gastroenterology; Disease; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001637855,0.0001923933,0.0004378364,0.0008430126,0.0003411734,0.0005101925,0.0001705423,0.0003333948,0.0009734186],"category_scores_gemma":[0.003211365,0.0001908636,0.0006093796,0.000998312,0.0003171207,0.0004875231,0.0002907296,0.0003323279,0.0001622203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003349063,"about_ca_system_score_gemma":0.0003072424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071547,"about_ca_topic_score_gemma":0.001025372,"domain_scores_codex":[0.9989561,0.0002646905,0.0002953093,0.0001924326,0.0002010835,0.00009030557],"domain_scores_gemma":[0.9950068,0.0009741185,0.00286794,0.0003216837,0.0004501813,0.0003792205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002959698,0.0000261828,0.9984073,0.00001895798,0.00007048494,0.00008331492,0.00003579283,0.00001826444,0.00008367348,0.000007787175,0.00002640678,0.0009257797],"study_design_scores_gemma":[0.00003792352,0.0012486,0.9960276,0.00002260029,0.000192922,0.001412553,0.0002285058,0.0001240011,0.0001598791,0.00002010959,0.0005181438,0.000007171725],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984568,0.001010337,0.00008197836,0.00001421838,0.000003945118,0.00001464575,0.0001821582,0.000001233135,0.0002347039],"genre_scores_gemma":[0.9994177,0.0002184984,0.00007285298,0.00002521949,0.00001096724,0.00001159749,0.0002016545,8.004815e-7,0.00004070986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001637855,"threshold_uncertainty_score":0.008661926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002118930694247457,"score_gpt":0.2079122551042341,"score_spread":0.2057933244099867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}