{"id":"W4293728835","doi":"10.1038/s42003-022-03559-7","title":"Subtype and cell type specific expression of lncRNAs provide insight into breast cancer","year":2022,"lang":"en","type":"article","venue":"Communications Biology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Fru Berta Kamprads Stiftelse; Biltema Foundation; Lunds Universitet; Mats Paulssons Stiftelse; Swedish Cancer Foundation; Kreftforeningen","keywords":"Biology; Breast cancer; Chromatin; Transcription factor; Transcriptional regulation; Computational biology; Gene expression; Cancer research; Gene; DNA methylation; Long non-coding RNA; Regulation of gene expression; Promoter; PRC2; Population; Genetics; Cancer; EZH2; RNA; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603695,0.00009248729,0.000119689,0.00008150777,0.0002405701,0.000006403756,0.0006384765,0.00009978397,0.000126735],"category_scores_gemma":[0.00002183371,0.0000930629,0.00003499792,0.0002025653,0.0002255281,0.000002687969,0.00160886,0.0002270808,0.000003214673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004081395,"about_ca_system_score_gemma":0.0001802181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001532046,"about_ca_topic_score_gemma":0.00007807903,"domain_scores_codex":[0.9990495,0.0003103263,0.0001759634,0.0002435386,0.0000714394,0.0001492718],"domain_scores_gemma":[0.9985726,0.00002459977,0.0001035411,0.001113591,0.000135381,0.00005030377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001169123,0.00007910135,0.0004734995,0.00001120756,0.00001456328,3.139703e-7,0.0001232694,0.00003311706,0.9933717,0.0007432512,0.0008718115,0.004161281],"study_design_scores_gemma":[0.0004017142,0.0002885679,0.0004405008,0.000007729433,0.000009117215,0.00001936776,0.0001137596,0.00007691759,0.5580953,0.0002316096,0.4401859,0.0001295067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8234233,0.1556191,0.003434171,0.004181498,0.0006444821,0.001344551,0.000424369,0.00005363035,0.01087495],"genre_scores_gemma":[0.9879252,0.009843379,0.001395171,0.0001031883,0.00003291183,0.0001196519,0.0003080122,0.00001882684,0.0002537024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4393141,"threshold_uncertainty_score":0.3794995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02203676403491841,"score_gpt":0.3038417969934993,"score_spread":0.2818050329585809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}