{"id":"W4293776153","doi":"10.3390/curroncol29090492","title":"Tobacco Use and Response to Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Cancer","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Lung cancer; Immune system; Cancer research; Immune checkpoint; Cancer; Immunology; Oncology; Bioinformatics; Immunotherapy; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02596124,0.0002462939,0.001575931,0.001022324,0.0003145879,0.001551929,0.0008002677,0.0008471003,0.001410473],"category_scores_gemma":[0.03917412,0.0002498263,0.002263242,0.002606678,0.0004741004,0.001177393,0.0006888598,0.001917068,0.000269172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001102496,"about_ca_system_score_gemma":0.002210123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006911378,"about_ca_topic_score_gemma":0.01160458,"domain_scores_codex":[0.9869572,0.008432798,0.002048601,0.0006478869,0.001575293,0.0003383041],"domain_scores_gemma":[0.9580649,0.02293399,0.01043379,0.002302647,0.005336122,0.0009285646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002201119,0.0002623043,0.8324713,0.004606684,0.002986021,0.0001062961,0.0003358072,0.0003711982,0.0004856984,0.0006150686,0.004491798,0.1510666],"study_design_scores_gemma":[0.0001573395,0.0009102602,0.977239,0.002429587,0.002582476,0.0002151034,0.0003163326,0.0008517395,0.0003974774,0.00118209,0.01368175,0.00003694099],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.378381,0.5730862,0.006676469,0.02345525,0.001928922,0.001483517,0.00772311,0.000124465,0.007141095],"genre_scores_gemma":[0.8767958,0.09797376,0.007020816,0.008717526,0.002150568,0.001056773,0.004784862,0.00005919477,0.001440738],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02596124,"threshold_uncertainty_score":0.1372977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.142498948949217,"score_gpt":0.4288219183545983,"score_spread":0.2863229694053813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}