{"id":"W4294051557","doi":"10.1016/j.jtct.2022.08.030","title":"Favorable Outcomes with R-CHOP Induction and Consolidative Autologous Stem Cell Transplantation for Double-Hit Lymphoma","year":2022,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta; Alberta Health Services","funders":"Gilead Sciences; Merck; AstraZeneca; Novartis; Eisai Canada; Pfizer; Bristol-Myers Squibb","keywords":"Medicine; Autologous stem-cell transplantation; CHOP; Induction chemotherapy; Internal medicine; Oncology; International Prognostic Index; Transplantation; Lymphoma; Diffuse large B-cell lymphoma; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003443277,0.000138231,0.0002404768,0.0002192586,0.0002802043,0.0004284747,0.0001567284,0.0001737788,0.0004579784],"category_scores_gemma":[0.001394593,0.00008927022,0.000144364,0.0002914348,0.0003449919,0.0002184934,0.0002816291,0.0002258096,0.0001076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007668611,"about_ca_system_score_gemma":0.0005288351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008048831,"about_ca_topic_score_gemma":0.01726425,"domain_scores_codex":[0.9997633,0.00004797025,0.00001540285,0.00003870283,0.00005649965,0.00007809581],"domain_scores_gemma":[0.9993349,0.00009345058,0.000234709,0.00003100448,0.0000647675,0.0002411687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005799317,0.00006810449,0.9902232,0.000007605916,0.00003429284,0.000615288,0.0001186736,0.0002006111,0.0007626934,0.00001995001,0.0001533794,0.007216427],"study_design_scores_gemma":[0.00004381008,0.0006758092,0.9968235,0.000005214072,0.00002373688,0.001507012,0.000158367,0.0003414154,0.0001343624,0.00002657677,0.0002555621,0.000004525772],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994627,0.0001645506,0.00003892458,0.00001769126,0.000002622339,0.000005250566,0.00003260948,0.000002193337,0.0002735326],"genre_scores_gemma":[0.9997392,0.00004227614,0.00001883976,0.00001383029,0.000006461941,0.000002041871,0.0001297396,6.801418e-7,0.00004689527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008048831,"threshold_uncertainty_score":0.01600397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02328548444801918,"score_gpt":0.2520073209841107,"score_spread":0.2287218365360915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}