{"id":"W4294233687","doi":"10.1038/s41598-022-19103-w","title":"Effect of MA01 rhamnolipid on cell viability and expression of quorum-sensing (QS) genes involved in biofilm formation by methicillin-resistant Staphylococcus aureus","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute for Genetic Engineering and Biotechnology","keywords":"Rhamnolipid; Biofilm; Quorum sensing; Microbiology; Viability assay; Pseudomonas aeruginosa; Staphylococcus aureus; Bacteria; Membrane permeability; Biology; Flow cytometry; Bacterial cell structure; Chemistry; Cell; Biochemistry; Membrane; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186797,0.0004348427,0.0002333954,0.0001482989,0.0001121141,0.0002619105,0.0001469376,0.0003059562,0.0007750405],"category_scores_gemma":[0.0003632859,0.0001037093,0.0001701014,0.0001266229,0.0001367034,0.0002033038,0.0002138959,0.0004266642,0.0002214101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001201551,"about_ca_system_score_gemma":0.0001561297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008470846,"about_ca_topic_score_gemma":0.0009208452,"domain_scores_codex":[0.9997846,0.00007496836,0.0000245772,0.00002567335,0.00005919709,0.00003094247],"domain_scores_gemma":[0.9997206,0.0001233654,0.00005080687,0.00002463443,0.00004177713,0.00003878173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009896585,0.00003799004,0.00007557405,0.00002134597,0.000003089179,0.00002130253,0.00001876222,0.00002448925,0.9991134,0.00001335836,0.00001144774,0.0005602505],"study_design_scores_gemma":[0.000007252833,0.000525394,0.00200319,0.000005143956,0.000007994385,0.00004750945,0.00002714401,0.0003418861,0.9965408,0.00001050138,0.0004787516,0.000004338905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971265,0.001395065,0.0004639132,0.0000720221,0.00001695841,0.00001474323,0.000177236,0.00001589859,0.0007176215],"genre_scores_gemma":[0.9957629,0.0007612639,0.00140594,0.00006005014,0.00001039942,0.00002935138,0.0004398723,0.00001132808,0.001518681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008470846,"threshold_uncertainty_score":0.002592742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00790988620864018,"score_gpt":0.2322207802606504,"score_spread":0.2243108940520102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}