{"id":"W4294293444","doi":"10.3390/pharmaceutics14091831","title":"PEG Conjugated Zein Nanoparticles for In Vivo Use","year":2022,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Innovation Council; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Cancer Foundation; University of British Columbia; NanoMedicines Innovation Network","keywords":"PEG ratio; Polyethylene glycol; In vivo; Chemistry; Conjugated system; Nanoparticle; Biophysics; PEGylation; Pharmacokinetics; Biochemistry; Pharmacology; Organic chemistry; Nanotechnology; Polymer; Materials science; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002186161,0.0005861869,0.0002413,0.0002972619,0.0001368514,0.0002447804,0.000271804,0.0006869324,0.002956907],"category_scores_gemma":[0.000136159,0.0002261411,0.000293891,0.0001390939,0.0001639896,0.0003567738,0.0002181141,0.0006935397,0.001293957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002646521,"about_ca_system_score_gemma":0.0001777968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003612202,"about_ca_topic_score_gemma":0.0006110732,"domain_scores_codex":[0.9998983,0.0000135177,0.000006886754,0.00002908779,0.00003370261,0.00001846943],"domain_scores_gemma":[0.9999387,0.000008884858,0.00001838554,0.00001212378,0.00001300004,0.000008954893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009493108,0.00003121631,0.00003325816,0.00005070969,0.000004320785,0.00004043819,0.00001115329,0.00009804311,0.9956382,0.0001308686,0.0001984518,0.003668512],"study_design_scores_gemma":[0.00002083025,0.0002764215,0.0003175426,0.000009287104,0.00001429519,0.0001736724,0.000008236947,0.0007164852,0.99103,0.00008403072,0.007344932,0.00000431855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6850547,0.0121227,0.2658715,0.0009609475,0.0007204581,0.001844228,0.004208927,0.003239319,0.02597729],"genre_scores_gemma":[0.9020998,0.006440824,0.06154285,0.0002951089,0.00004725661,0.001332797,0.002252616,0.0002621473,0.02572663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002956907,"threshold_uncertainty_score":0.009891808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07050132323855292,"score_gpt":0.326724523835274,"score_spread":0.256223200596721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}