{"id":"W4294440121","doi":"10.1093/function/zqac043","title":"Noncanonical Role of Telomerase in Regulation of Microvascular Redox Environment With Implications for Coronary Artery Disease","year":2022,"lang":"en","type":"article","venue":"Function","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; University of South Alabama; National Institute of General Medical Sciences; American Heart Association","keywords":"Telomerase; Mitochondrion; Mitochondrial DNA; Biology; Reactive oxygen species; Telomerase reverse transcriptase; Nitric oxide; Cell biology; Biochemistry; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001659133,0.000222372,0.0001671275,0.0001404327,0.0001447144,0.0004358276,0.0001624818,0.0002833807,0.001056705],"category_scores_gemma":[0.0001937255,0.00008549605,0.0001603482,0.00007866448,0.0002505099,0.0001803734,0.0001759538,0.0004108149,0.0001373506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001609084,"about_ca_system_score_gemma":0.000106144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001221881,"about_ca_topic_score_gemma":0.000155495,"domain_scores_codex":[0.9999371,0.00001249439,0.000004872093,0.00001757418,0.00001183553,0.00001619105],"domain_scores_gemma":[0.999861,0.00002213068,0.00004766901,0.00001797599,0.00002076884,0.00003039653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002572084,0.00003491127,0.005277146,0.00009134475,0.00002048122,0.0006731153,0.0000568374,0.00008718346,0.9873419,0.001310973,0.0001219418,0.004727055],"study_design_scores_gemma":[0.0001884388,0.0021804,0.2271367,0.0001853987,0.0002395728,0.0121274,0.0008710058,0.005919494,0.7198818,0.01040242,0.02082664,0.00004064625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767076,0.01504037,0.005117188,0.0007783297,0.0001558855,0.00001324358,0.0001460298,0.00008450232,0.001956789],"genre_scores_gemma":[0.9969368,0.001685994,0.0005892015,0.00004893805,0.00004333162,0.000007268423,0.00004154237,0.00000357156,0.0006432727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001056705,"threshold_uncertainty_score":0.003535032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008962738112736453,"score_gpt":0.2126453780346299,"score_spread":0.2036826399218934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}