{"id":"W4294683598","doi":"10.1093/neuonc/noac174.222","title":"P11.33.B Tumour Treating Fields (TTFields; 200 kHz) with chemo-radiation and maintenance TTFields/temozolomide as first-line treatment for newly-diagnosed glioblastoma: The phase 3 TRIDENT Trial (EF-32)","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Temozolomide; Medicine; Internal medicine; Oncology; Clinical endpoint; Clinical trial; Concomitant; Phases of clinical research; Cancer; Adverse effect; Progression-free survival; Radiation therapy; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009807766,0.0008465338,0.0009996092,0.0003408307,0.0003195815,0.0006730843,0.0005142672,0.000918401,0.01036578],"category_scores_gemma":[0.0004152205,0.0003197137,0.0007508823,0.0003388801,0.0006058753,0.0005629607,0.0002699322,0.002415588,0.001690942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006210941,"about_ca_system_score_gemma":0.001189401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00112622,"about_ca_topic_score_gemma":0.003137882,"domain_scores_codex":[0.999824,0.00006491858,0.000008625939,0.00003514803,0.00002057519,0.00004683042],"domain_scores_gemma":[0.9997464,0.00002506275,0.00005305431,0.0000176865,0.00001812282,0.0001396569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7871776,0.02254838,0.003007519,0.001420618,0.0009663836,0.0002605082,0.0001272019,0.001544702,0.04245086,0.001056769,0.0201834,0.1192561],"study_design_scores_gemma":[0.7077652,0.2597795,0.008956508,0.0001664885,0.0006361994,0.0005090396,0.00006105484,0.00121493,0.004725558,0.00102084,0.01512638,0.00003840792],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.969705,0.007109216,0.001084686,0.001851248,0.000544877,0.004757959,0.005780438,0.00037894,0.00878751],"genre_scores_gemma":[0.9626697,0.004340883,0.002949261,0.00248927,0.0002526442,0.006704944,0.00767876,0.0001013268,0.01281321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01036578,"threshold_uncertainty_score":0.03467703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02202927441482746,"score_gpt":0.3144258127881759,"score_spread":0.2923965383733484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}