{"id":"W4294718687","doi":"10.1177/26331055221123346","title":"Mutations in the Spliceosome Component <i>prp-6</i> and Overexpression of <i>cdh-5</i> Suppress Axon Guidance Defects of <i>cdh-4</i> Mutants in <i>Caenorhabditis elegans</i>","year":2022,"lang":"en","type":"article","venue":"Neuroscience Insights","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Caenorhabditis elegans; Biology; Mutant; Axon guidance; Cell biology; Axon; Loss function; Mutation; Fasciculation; Ventral nerve cord; Genetics; Netrin; Gene; Nervous system; Neuroscience; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007916521,0.0007385939,0.0002041632,0.0005138047,0.0002511248,0.0002524966,0.0003731492,0.0003621501,0.001133642],"category_scores_gemma":[0.00008948577,0.0002631625,0.0002300066,0.0001515013,0.0004230147,0.0001323468,0.0003332362,0.0005799601,0.0006190892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004674693,"about_ca_system_score_gemma":0.0003030633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001605374,"about_ca_topic_score_gemma":0.004656882,"domain_scores_codex":[0.9998697,0.00001095493,0.00001502587,0.00002850957,0.00005523031,0.0000205664],"domain_scores_gemma":[0.9998311,0.00001924013,0.00006566969,0.00001356579,0.0000115322,0.00005879368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002656433,0.00001812713,0.0001295628,0.00001999303,0.000004142089,0.00007907775,0.000004301398,0.00007406306,0.9990619,0.00006728878,0.00003546326,0.000479497],"study_design_scores_gemma":[0.00001703635,0.00007564851,0.006307765,0.00001032787,0.00002053979,0.0004829192,0.00001886267,0.001340931,0.9895593,0.00005236392,0.00210558,0.000008781428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910014,0.0009064745,0.003667544,0.0001061301,0.00003841432,0.00004155297,0.0008141479,0.0003047002,0.003119671],"genre_scores_gemma":[0.9830444,0.0007803491,0.006697389,0.0001033918,0.00001525818,0.00005526329,0.001336831,0.0001622436,0.007804942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001605374,"threshold_uncertainty_score":0.003792465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01101562310779932,"score_gpt":0.2311286452593438,"score_spread":0.2201130221515445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}