{"id":"W4294775247","doi":"10.3233/tub-220006","title":"Induction of alternative NF- <i>κ</i> B within TAg-induced basal mammary tumors in activation-resistant inhibitor of <i>κ</i> -B kinase (IKKα) mutant mice","year":2022,"lang":"en","type":"article","venue":"Tumor Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Margaret A. Cargill Foundation","keywords":"Mutant; IκB kinase; Basal (medicine); Kinase; NF-κB; Cancer research; NFKB1; Cell biology; Biology; Molecular biology; Chemistry; Signal transduction; Gene; Transcription factor; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005809955,0.0002314775,0.0003839514,0.000217744,0.00007416159,0.000004714852,0.0004046523,0.0001094095,0.00002651183],"category_scores_gemma":[0.0002011121,0.0002399489,0.0001048673,0.0003592834,0.0001514166,0.000009766416,0.0003748551,0.0003040848,0.000001317005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008171191,"about_ca_system_score_gemma":0.000317505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006275619,"about_ca_topic_score_gemma":0.00006277342,"domain_scores_codex":[0.9978718,0.0004133376,0.0006901741,0.0005364949,0.0001912033,0.0002969546],"domain_scores_gemma":[0.9987381,0.00005527368,0.0006160011,0.0003995874,0.0001300144,0.00006101048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006958845,0.0002480478,0.001326244,0.00003491072,0.00004346325,0.00002886697,0.0002479584,0.000319529,0.9959754,0.0008334638,0.0000921314,0.0001541261],"study_design_scores_gemma":[0.001095781,0.001362502,0.0007780213,0.00003239954,0.00001042224,0.0000320429,0.0004158481,0.00007457126,0.9948297,0.0007603639,0.0003725438,0.0002357792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983923,0.0001141664,0.0001663991,0.0001759045,0.0004283717,0.0003412813,0.0001889263,0.00001438187,0.0001782123],"genre_scores_gemma":[0.9987198,0.000006363529,0.0004560805,0.0002766647,0.0001480299,0.0000902199,0.0002423377,0.00003150821,0.00002898513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001145649,"threshold_uncertainty_score":0.9784831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0153015559835997,"score_gpt":0.2442497285394181,"score_spread":0.2289481725558184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}