{"id":"W4294775247","doi":"10.3233/tub-220006","title":"Induction of alternative NF- <i>κ</i> B within TAg-induced basal mammary tumors in activation-resistant inhibitor of <i>κ</i> -B kinase (IKKα) mutant mice","year":2022,"lang":"en","type":"article","venue":"Tumor Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Margaret A. Cargill Foundation","keywords":"Mutant; IκB kinase; Basal (medicine); Kinase; NF-κB; Cancer research; NFKB1; Cell biology; Biology; Molecular biology; Chemistry; Signal transduction; Gene; Transcription factor; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003765023,0.00092278,0.0003673533,0.0008518334,0.0002847467,0.0005726822,0.000569805,0.0006970586,0.00287277],"category_scores_gemma":[0.0001871896,0.000449945,0.000737734,0.0003087184,0.0006005298,0.0003795359,0.0003116305,0.001636044,0.001467024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006194147,"about_ca_system_score_gemma":0.0003387961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005874131,"about_ca_topic_score_gemma":0.0008724498,"domain_scores_codex":[0.9994929,0.0000644385,0.00007893001,0.0001088493,0.0001387485,0.0001162044],"domain_scores_gemma":[0.9990669,0.00007423286,0.0003908025,0.0001200509,0.00004622579,0.0003018506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002244588,0.0001086856,0.0001462982,0.00003079574,0.000006649048,0.00006667154,0.00001565204,0.00006763298,0.9986552,0.0001477337,0.0000531228,0.0004770411],"study_design_scores_gemma":[0.0001061514,0.000768941,0.00323831,0.00002075811,0.0000254194,0.0006778064,0.00004565036,0.0011856,0.9912497,0.0001071308,0.002564007,0.00001065928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841105,0.0008193395,0.008428578,0.0002538212,0.0001125022,0.0002544276,0.002760905,0.0007339792,0.00252586],"genre_scores_gemma":[0.9787695,0.0008294916,0.007541509,0.0001150109,0.00003695213,0.0002942182,0.002636629,0.0002409166,0.009535735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00287277,"threshold_uncertainty_score":0.009610355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0153015559835997,"score_gpt":0.2442497285394181,"score_spread":0.2289481725558184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}