{"id":"W4294958737","doi":"10.1016/j.bbr.2022.114107","title":"A promising mouse model for Friedreich Ataxia progressing like human patients","year":2022,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Ataxia UK; Ataxia Canada; National Ataxia Foundation","keywords":"Frataxin; Ataxia; Genetically modified mouse; Transgene; Biology; Disease; Neuroscience; Gene; Genetics; Medicine; Pathology; Iron-binding proteins","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009417049,0.001681925,0.0007034038,0.002251852,0.00102354,0.0009818943,0.0012797,0.00213264,0.01094785],"category_scores_gemma":[0.0003857888,0.0004800549,0.001144473,0.0008278212,0.0008766593,0.001026552,0.000611957,0.00210968,0.003172663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004921939,"about_ca_system_score_gemma":0.0006480434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001295915,"about_ca_topic_score_gemma":0.002895002,"domain_scores_codex":[0.9995023,0.0001068801,0.00008865711,0.0001358934,0.00009289352,0.0000733078],"domain_scores_gemma":[0.9995702,0.0000695613,0.0001157725,0.00006802526,0.00005756312,0.0001188495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001159046,0.0006492851,0.0009054443,0.0002188026,0.0001362238,0.00221672,0.0001908656,0.0003921505,0.9784546,0.006172554,0.003565265,0.005938932],"study_design_scores_gemma":[0.001729541,0.003910202,0.009761117,0.0004236988,0.001168263,0.01746052,0.0005506809,0.003729531,0.8001842,0.005748468,0.1551893,0.0001445785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8718817,0.006226221,0.06180653,0.005079102,0.001572758,0.002069973,0.02930141,0.003419694,0.01864269],"genre_scores_gemma":[0.8252013,0.009377912,0.06213452,0.001649925,0.0002332492,0.002757455,0.0230841,0.000881659,0.07468001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01094785,"threshold_uncertainty_score":0.03662419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2688926457228425,"score_gpt":0.4275996752341557,"score_spread":0.1587070295113132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}