{"id":"W4295009342","doi":"10.1016/j.drugalcdep.2022.109606","title":"Efficacy of ketamine intervention to decrease alcohol use, cravings, and withdrawal symptoms in adults with problematic alcohol use or alcohol use disorder: A systematic review and comprehensive analysis of mechanism of actions.","year":2022,"lang":"en","type":"review","venue":"Drug and Alcohol Dependence","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Université de Montréal; Douglas Mental Health University Institute; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"","keywords":"Systematic review; Medicine; CINAHL; PsycINFO; Psychological intervention; Ketamine; Psychiatry; Alcohol use disorder; Alcohol dependence; Intervention (counseling); MEDLINE; Randomized controlled trial; Meta-analysis; Craving; Alcohol withdrawal syndrome; Acamprosate; Alcohol; Addiction; Naltrexone; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006789309,0.001272803,0.009153516,0.004368145,0.0005926298,0.001847954,0.001295233,0.001810569,0.003189712],"category_scores_gemma":[0.02402553,0.0008152651,0.01111948,0.003361874,0.0007026246,0.001465918,0.001073322,0.001269481,0.0001897248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002781392,"about_ca_system_score_gemma":0.008432188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005014424,"about_ca_topic_score_gemma":0.01725439,"domain_scores_codex":[0.9951303,0.001860837,0.001701016,0.0003534927,0.0008185791,0.0001358777],"domain_scores_gemma":[0.9865094,0.008747463,0.003232399,0.0002078753,0.001087743,0.0002151504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.001025123,0.00006643347,0.0006798133,0.9323158,0.02016539,0.00005557477,0.0001332939,0.00008432921,0.0002345545,0.0001070684,0.000589519,0.0445431],"study_design_scores_gemma":[0.002527172,0.002074738,0.009306388,0.6920933,0.2801563,0.0004335931,0.0003185835,0.0002178548,0.0005142555,0.0002987621,0.01199389,0.00006511747],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002344954,0.9965564,0.00009761651,0.0001407757,0.00006593591,0.0004576243,0.0001635578,0.000006903216,0.0001663206],"genre_scores_gemma":[0.04021385,0.9570421,0.001014213,0.0004180211,0.00007738854,0.0009334427,0.0001717847,0.000004990505,0.0001241009],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009153516,"threshold_uncertainty_score":0.03590572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05218281042729794,"score_gpt":0.3341008435881068,"score_spread":0.2819180331608088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}