{"id":"W4295037641","doi":"10.1021/acsinfecdis.2c00157","title":"Effect of Lipid Length and Cationic Residues on the Antibacterial and Hemolytic Activities of Paenibacterin","year":2022,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Hemolysis; Cationic polymerization; Bacillus subtilis; Klebsiella pneumoniae; Chemistry; Antibacterial activity; Acinetobacter baumannii; Escherichia coli; Pseudomonas aeruginosa; Microbiology; Minimum inhibitory concentration; Biochemistry; Bacteria; Antibiotics; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893582,0.0003884818,0.0002336673,0.0001303706,0.00008507608,0.0002880487,0.0002049762,0.0002590115,0.0008498997],"category_scores_gemma":[0.0004293464,0.0001442541,0.0001462479,0.0001311768,0.0002030201,0.0002515333,0.0001940882,0.0004868978,0.0002103677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001393941,"about_ca_system_score_gemma":0.0001784106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004881423,"about_ca_topic_score_gemma":0.0004457337,"domain_scores_codex":[0.9998016,0.0000657202,0.00002413472,0.0000288173,0.00004134893,0.00003845042],"domain_scores_gemma":[0.9995764,0.0001648953,0.0001012081,0.00002827145,0.00005370416,0.00007551078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005664021,0.00006775203,0.0002240723,0.00003376169,0.000007687777,0.00003409893,0.00001743561,0.0001538987,0.9978404,0.00001901511,0.00001331493,0.001022045],"study_design_scores_gemma":[0.00002130863,0.001102875,0.002578592,0.000008852627,0.00002063699,0.00008862338,0.0000248172,0.000527226,0.9949905,0.00001280273,0.0006144165,0.000009272449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987833,0.0004853232,0.0001897844,0.0000224962,0.000007877178,0.000007233905,0.00006281351,0.00000641429,0.0004347282],"genre_scores_gemma":[0.9985556,0.0003328747,0.0005591518,0.00003476495,0.000005661179,0.000008122871,0.0001341401,0.00000724786,0.0003623381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008498997,"threshold_uncertainty_score":0.002843201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004690331508140496,"score_gpt":0.2119571889516303,"score_spread":0.2072668574434898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}