{"id":"W4295037641","doi":"10.1021/acsinfecdis.2c00157","title":"Effect of Lipid Length and Cationic Residues on the Antibacterial and Hemolytic Activities of Paenibacterin","year":2022,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Hemolysis; Cationic polymerization; Bacillus subtilis; Klebsiella pneumoniae; Chemistry; Antibacterial activity; Acinetobacter baumannii; Escherichia coli; Pseudomonas aeruginosa; Microbiology; Minimum inhibitory concentration; Biochemistry; Bacteria; Antibiotics; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001470068,0.000124729,0.0002540203,0.0000674343,0.0003288502,0.00001473556,0.00007509219,0.00003855096,0.0002238236],"category_scores_gemma":[0.00009495951,0.00009022066,0.00005319252,0.00006071166,0.0004290251,0.00007249098,0.0001516928,0.000128822,0.00000151854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001703861,"about_ca_system_score_gemma":0.00003218909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001256318,"about_ca_topic_score_gemma":0.00001130874,"domain_scores_codex":[0.9991665,0.0003710896,0.0001472775,0.0001525775,0.00003199021,0.0001304958],"domain_scores_gemma":[0.998845,0.0008292989,0.0001446228,0.0001561289,0.0000142355,0.00001065806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001453938,0.0003475888,0.09011246,0.0003221026,0.0003918995,0.000002217535,0.0008007413,0.00001521863,0.8916264,0.002703534,0.001433892,0.01079008],"study_design_scores_gemma":[0.00190735,0.004381852,0.115259,0.00008208436,0.0002497233,0.00009948862,0.0006596428,0.000001473566,0.8753368,0.0002973772,0.001454674,0.000270515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983675,0.0004831927,7.761805e-7,0.0000770113,0.0002481852,0.0002093716,0.0002551413,0.0000273988,0.0003314007],"genre_scores_gemma":[0.9994426,0.0002234524,4.465362e-7,0.00005207861,0.00003162541,0.0000262673,0.00002681578,0.00001101297,0.0001857329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02514651,"threshold_uncertainty_score":0.3679092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004690331508140496,"score_gpt":0.2119571889516303,"score_spread":0.2072668574434898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}