{"id":"W4295066965","doi":"10.1007/s43441-022-00453-6","title":"Pediatric Clinical Research Networks: Role in Accelerating Development of Therapeutics in Children","year":2022,"lang":"en","type":"review","venue":"Therapeutic Innovation & Regulatory Science","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research; U.S. Food and Drug Administration; Genome Canada; U.S. Department of Health and Human Services","keywords":"Context (archaeology); Interoperability; Benchmarking; Process management; Timeline; Legislation; Biopharmaceutical; Quality (philosophy); Business; Knowledge management; Medicine; Computer science; Political science; Marketing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.005772146,0.0008413731,0.001198704,0.003672982,0.0003084145,0.00209485,0.001043516,0.001691297,0.007119484],"category_scores_gemma":[0.007887042,0.0002571466,0.0008519735,0.004073146,0.0008135685,0.001879975,0.001566579,0.002399202,0.001098785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002462939,"about_ca_system_score_gemma":0.008996887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002548577,"about_ca_topic_score_gemma":0.005900283,"domain_scores_codex":[0.998262,0.0007434681,0.0002315523,0.0001718284,0.0004555421,0.0001355865],"domain_scores_gemma":[0.9900809,0.006975019,0.001382265,0.0001443954,0.001024173,0.0003932948],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007377807,0.00006386579,0.000575792,0.02977094,0.0002227465,0.0001061256,0.00007408421,0.0003104209,0.0003529641,0.01333142,0.02157678,0.9335411],"study_design_scores_gemma":[0.00006608241,0.00009594973,0.001817082,0.03996203,0.0004638882,0.0004799775,0.0001174259,0.0001002009,0.0003269799,0.004324606,0.9522296,0.00001641896],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008910512,0.9969742,0.0001833754,0.001315234,0.000181538,0.00001239142,0.0000322698,0.000006922325,0.001204892],"genre_scores_gemma":[0.001091821,0.997133,0.0005687636,0.0007021191,0.0001804953,0.00001749391,0.00003193326,0.00000155805,0.0002728292],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9942278,"threshold_uncertainty_score":0.0305264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.484866045612045,"score_gpt":0.5439245465786663,"score_spread":0.05905850096662124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}