{"id":"W4295124073","doi":"10.3389/fphar.2022.969500","title":"Insula deep rTMS and varenicline for smoking cessation: A randomized control trial study protocol","year":2022,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Family Medicine; Research Canada; Canadian Institutes of Health Research; University of Toronto; Ontario Brain Institute; Centre for Addiction and Mental Health","funders":"BrainsWay; Pfizer","keywords":"Varenicline; Insula; Abstinence; Smoking cessation; Medicine; Nicotine; Randomized controlled trial; Nicotine patch; Craving; Clinical trial; Transcranial magnetic stimulation; Anesthesia; Psychiatry; Addiction; Psychology; Placebo; Internal medicine; Stimulation; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01297001,0.006164424,0.01055586,0.001532331,0.002688058,0.002302576,0.002888485,0.005696574,0.04894263],"category_scores_gemma":[0.009273488,0.0023747,0.003081412,0.001729917,0.003057546,0.002261947,0.001180104,0.005450136,0.008751454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002301163,"about_ca_system_score_gemma":0.01034217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00173513,"about_ca_topic_score_gemma":0.003893245,"domain_scores_codex":[0.9933463,0.003446894,0.0005315258,0.0009031207,0.000785234,0.0009868937],"domain_scores_gemma":[0.9959545,0.0009203858,0.0008146755,0.000476239,0.0007809619,0.001053144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9620772,0.01400787,0.0004397887,0.003682829,0.0007826958,0.0001032621,0.00008537791,0.0005755737,0.001534955,0.000819122,0.00482721,0.01106395],"study_design_scores_gemma":[0.9631277,0.02717808,0.0009681404,0.0003081156,0.0004980652,0.00002843605,0.00002577113,0.0008151075,0.000320738,0.0006551684,0.006030795,0.00004389346],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0166031,0.000915057,0.002735564,0.0005518884,0.0008754547,0.9740519,0.002295904,0.0002116998,0.001759408],"genre_scores_gemma":[0.01287168,0.0003855769,0.003165092,0.0004820328,0.0002137961,0.9805204,0.0004425766,0.00001438688,0.001904411],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04894263,"threshold_uncertainty_score":0.1637294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03419257592991608,"score_gpt":0.3588690840396211,"score_spread":0.324676508109705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}