{"id":"W4295226684","doi":"10.1016/s0090-8258(22)01548-7","title":"ARTISTRY-7: A phase 3, multicenter study of nemvaleukin alfa, a novel engineered cytokine, in combination with pembrolizumab versus chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer (326)","year":2022,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Pembrolizumab; Oncology; Internal medicine; Tolerability; Ovarian cancer; Carboplatin; Chemotherapy; Fallopian tube; Bevacizumab; Cancer; Immunotherapy; Cisplatin; Surgery; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001699545,0.001275235,0.001691765,0.0003680961,0.0003995319,0.00105151,0.0008917056,0.001356312,0.002533971],"category_scores_gemma":[0.000844432,0.0004343664,0.001733842,0.0003300517,0.0009566488,0.0008421619,0.0003237561,0.003770085,0.0006988891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007266589,"about_ca_system_score_gemma":0.001393423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009453006,"about_ca_topic_score_gemma":0.002739813,"domain_scores_codex":[0.9996299,0.0001943616,0.00001479027,0.00004937198,0.00003295064,0.00007856651],"domain_scores_gemma":[0.9994707,0.00009391601,0.00009022026,0.00004462357,0.00003627476,0.0002643901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8267969,0.05854904,0.005593624,0.00104867,0.002890188,0.0001754561,0.0003442299,0.002697628,0.03149907,0.000458025,0.00418083,0.06576632],"study_design_scores_gemma":[0.7081764,0.2784316,0.006704556,0.00003603958,0.0007990202,0.0001620305,0.00009298368,0.001078715,0.002292914,0.0001889484,0.002008111,0.0000286706],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915524,0.00248078,0.0005781194,0.0005966055,0.0002407998,0.001626646,0.001112568,0.00009619861,0.001715918],"genre_scores_gemma":[0.9861091,0.00235931,0.002110629,0.001465474,0.0002654913,0.002295567,0.002481265,0.00004106411,0.002872191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002533971,"threshold_uncertainty_score":0.008988202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01954682296436472,"score_gpt":0.2973953425600409,"score_spread":0.2778485195956762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}