{"id":"W4295226840","doi":"10.1016/s0090-8258(22)01519-0","title":"FLORA-5: A phase III double blind placebo controlled multicenter clinical study of front-line chemo-immunotherapy (paclitaxel and carboplatin +/- oregovomab) in patients with advanced epithelial ovarian cancer (GOG-3035) (298)","year":2022,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Medicine; Carboplatin; Paclitaxel; Oncology; Internal medicine; Placebo; Phases of clinical research; Immunotherapy; Ovarian cancer; Front line; Double blind; Clinical trial; Cancer; Chemotherapy; Pathology; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001451753,0.001982049,0.003341476,0.0008366246,0.0005973875,0.001124901,0.001403404,0.002037944,0.006863329],"category_scores_gemma":[0.0009544261,0.0007807431,0.001955681,0.0005150739,0.0013569,0.0008060914,0.0004173526,0.003982391,0.001510009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006475738,"about_ca_system_score_gemma":0.001799161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00156503,"about_ca_topic_score_gemma":0.003449894,"domain_scores_codex":[0.9996225,0.0001634671,0.00001950205,0.00006585265,0.00003237805,0.00009626365],"domain_scores_gemma":[0.9994376,0.0000940512,0.00008672521,0.00005069648,0.00003322319,0.0002975962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9307814,0.02823778,0.0008787547,0.0007272682,0.00110337,0.0000634541,0.00007790761,0.0004768592,0.009095034,0.0001670675,0.001712937,0.02667817],"study_design_scores_gemma":[0.894838,0.1018446,0.00154227,0.00001715351,0.0002531087,0.00002991058,0.00001914699,0.0002422555,0.00060655,0.00005079723,0.000545162,0.00001107338],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791052,0.004682172,0.001434169,0.0007932861,0.0006771073,0.00672656,0.002731893,0.0005941194,0.003255561],"genre_scores_gemma":[0.9691403,0.004126123,0.004271288,0.00253927,0.0007197129,0.007560798,0.004360856,0.00008412258,0.007197568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006863329,"threshold_uncertainty_score":0.02296013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03521650387064424,"score_gpt":0.3710703239255556,"score_spread":0.3358538200549113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}