{"id":"W4295532974","doi":"10.1111/all.15513","title":"Efficacy of <scp>FP</scp>‐025: A novel matrix metalloproteinase‐12 (<scp>MMP</scp>‐12) inhibitor in murine allergic asthma","year":2022,"lang":"en","type":"letter","venue":"Allergy","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Asthma; Immunology; Medicine; House dust mite; Bronchial hyperresponsiveness; Matrix metalloproteinase; Prednisone; Bronchoalveolar lavage; Eosinophilia; Pathophysiology; Pathophysiology of asthma; Allergy; Respiratory disease; Internal medicine; Allergen; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007845586,0.0008633729,0.0009801917,0.0001850926,0.0002659205,0.0004258633,0.0007005979,0.001121125,0.00191637],"category_scores_gemma":[0.0002971618,0.0001869354,0.0005017345,0.0001730306,0.0004697503,0.0003886742,0.0001334601,0.002845105,0.0007933828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004090975,"about_ca_system_score_gemma":0.0002450838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002661932,"about_ca_topic_score_gemma":0.0007218888,"domain_scores_codex":[0.9996213,0.00007268022,0.0000493252,0.00005548522,0.0001435568,0.00005756585],"domain_scores_gemma":[0.9995998,0.000123008,0.00009014212,0.00002547327,0.00007468064,0.00008695379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005079522,0.0009469148,0.0005626332,0.001113698,0.00006839681,0.001136553,0.00004547511,0.0001999802,0.9501068,0.0004439891,0.01110009,0.02919595],"study_design_scores_gemma":[0.001024839,0.01590987,0.005216935,0.0001116537,0.0003591688,0.003102948,0.0000688229,0.001994804,0.8771311,0.0001923433,0.09484263,0.00004485529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7649115,0.1632035,0.009612716,0.01852448,0.0322017,0.0005210892,0.002633226,0.0007979374,0.007593949],"genre_scores_gemma":[0.8751621,0.06990842,0.006976401,0.006124964,0.01084388,0.0003335102,0.001740071,0.00009840085,0.02881224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00191637,"threshold_uncertainty_score":0.006410897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01147005374658037,"score_gpt":0.2294049487345472,"score_spread":0.2179348949879669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}