{"id":"W4295559695","doi":"10.3390/biology11091341","title":"Hepatic Gene Expression Profiling of American Kestrels (Falco sparverius) Exposed In Ovo to Three Alternative Brominated Flame Retardants","year":2022,"lang":"en","type":"article","venue":"Biology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Environment and Climate Change Canada","funders":"Environment Canada; U.S. Geological Survey; Environment and Climate Change Canada","keywords":"DIO2; Biology; In ovo; Polybrominated diphenyl ethers; SOD1; Oxidative stress; Internal medicine; Gene expression; Downregulation and upregulation; Endocrinology; Gene; Thyroid; Cell biology; Superoxide dismutase; Genetics; Triiodothyronine; Deiodinase; Ecology; Embryo; Pollutant; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002865733,0.0001460657,0.0002987311,0.00009167618,0.00006038613,0.000003342195,0.0004178953,0.00003611322,0.001380601],"category_scores_gemma":[0.0001622576,0.0001330001,0.00003665864,0.000470484,0.0002112795,0.00005586326,0.0005720006,0.0001542181,0.00007032969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003703543,"about_ca_system_score_gemma":0.00002771335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001236043,"about_ca_topic_score_gemma":0.0003644058,"domain_scores_codex":[0.998505,0.0002236224,0.0003162954,0.0003943733,0.0001829477,0.000377779],"domain_scores_gemma":[0.999311,0.00007414666,0.0002049972,0.00030872,0.000001699874,0.00009938511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007373645,0.00007344783,0.1373316,9.646054e-7,0.000006627507,0.00001662597,0.0004692694,0.0002419297,0.8478633,0.00000266485,0.00001398989,0.01390592],"study_design_scores_gemma":[0.0003671195,0.0005558821,0.3588782,0.00000714416,0.000003775083,0.00001041132,0.0001757359,0.000673454,0.6389611,0.000169311,0.00005594892,0.0001419415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998623,0.00002088641,0.0003122422,0.00009616269,0.0001642039,0.0003553685,0.0001561631,0.00002573318,0.000246294],"genre_scores_gemma":[0.9953898,0.000006135605,0.004387285,0.0001103729,0.0000174523,0.00002733024,0.000005716659,0.00001765935,0.00003827663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2215466,"threshold_uncertainty_score":0.9995323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01887914111115406,"score_gpt":0.2596773747481687,"score_spread":0.2407982336370146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}