{"id":"W4295592689","doi":"10.3390/cells11182830","title":"Bioinformatic Analyses of Broad H3K79me2 Domains in Different Leukemia Cell Line Data Sets","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Biology; Gene; Chromatin; Genetics; Histone; Leukemia; H3K4me3; Phenotype; Computational biology; Cell biology; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009247243,0.0006070603,0.0006699239,0.002692668,0.0007301032,0.0007309755,0.000407516,0.0004264436,0.002521072],"category_scores_gemma":[0.001413977,0.0001905432,0.0008324779,0.002356115,0.000288199,0.0003012065,0.0004601784,0.0006382196,0.0009921489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004544389,"about_ca_system_score_gemma":0.000433874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00138151,"about_ca_topic_score_gemma":0.003471684,"domain_scores_codex":[0.9992402,0.00007958806,0.00008466427,0.0002985166,0.0002306581,0.00006643385],"domain_scores_gemma":[0.9989761,0.0004705246,0.000138724,0.0001170405,0.0001634867,0.0001340955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002615038,0.0006340786,0.09719948,0.002001759,0.0009295826,0.001778323,0.0009308112,0.005495131,0.7832975,0.0007902819,0.01232184,0.0920063],"study_design_scores_gemma":[0.0003288406,0.0007149762,0.5865706,0.0001236235,0.0007706783,0.003322452,0.001050081,0.09686179,0.2526811,0.002487972,0.0548573,0.0002307263],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8675509,0.001194354,0.02337575,0.0004028202,0.00009972371,0.0002056174,0.09801107,0.007012878,0.002146997],"genre_scores_gemma":[0.6451219,0.0005210376,0.06480876,0.000436144,0.00003291232,0.000475656,0.2858156,0.00126022,0.001527885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002692668,"threshold_uncertainty_score":0.008433819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02278167270099297,"score_gpt":0.2760482705681581,"score_spread":0.2532665978671652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}