{"id":"W4295678729","doi":"10.1128/jb.00185-22","title":"Pseudomonas aeruginosa Strains from Both Clinical and Environmental Origins Readily Adopt a Stable Small-Colony-Variant Phenotype Resulting from Single Mutations in c-di-GMP Pathways","year":2022,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Pseudomonas aeruginosa; Biology; Phenotype; Cystic fibrosis; Microbiology; Pathogen; Genetics; Mutation; Strain (injury); Pseudomonadaceae; Virulence; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418465,0.0002887592,0.0001859596,0.0002333037,0.0001799775,0.0003100906,0.0002412464,0.0003258643,0.0008827464],"category_scores_gemma":[0.0004246904,0.0001294546,0.0001881466,0.000206316,0.0002414608,0.0002197517,0.0005047353,0.0005219031,0.0003092012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000138356,"about_ca_system_score_gemma":0.0002313672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086388,"about_ca_topic_score_gemma":0.001464567,"domain_scores_codex":[0.9997081,0.00003322714,0.00002243048,0.00005362903,0.0001119083,0.00007065921],"domain_scores_gemma":[0.9997255,0.00003667906,0.00007733453,0.00005175389,0.00005357639,0.00005500165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003054414,0.00002209878,0.001199142,0.00001622928,0.000003164283,0.0001732843,0.00003057894,0.00001228558,0.9966428,0.00008982038,0.00007650843,0.001703558],"study_design_scores_gemma":[0.00003105042,0.0008828869,0.1012617,0.00002733858,0.00003276321,0.005395634,0.0005660751,0.0009403213,0.8831419,0.0005067784,0.00717984,0.00003375932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946913,0.0004824435,0.002420106,0.00023332,0.00002625749,0.00003404096,0.0002523313,0.00007061331,0.001789589],"genre_scores_gemma":[0.9971533,0.0001983492,0.001081056,0.00008472168,0.000006504605,0.0000240044,0.0002933458,0.00001401578,0.001144694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001086388,"threshold_uncertainty_score":0.002953053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0262143795815478,"score_gpt":0.2446257008647345,"score_spread":0.2184113212831867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}