{"id":"W4295681666","doi":"10.1111/exd.14675","title":"From simplicity to complexity in current melanoma models","year":2022,"lang":"en","type":"review","venue":"Experimental Dermatology","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Eurostars; Rijksdienst voor Ondernemend Nederland","keywords":"Melanoma; Tumor microenvironment; Computational biology; Translational research; Immunotherapy; Computer science; Biology; Cancer research; Immune system; Immunology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001200691,0.0004277227,0.001482818,0.0003919527,0.00006096085,0.00002796635,0.0008825798,0.0002440001,0.001925099],"category_scores_gemma":[0.00003777783,0.0004415287,0.0002139982,0.0004512141,0.0001135259,0.00005766058,0.0009867402,0.001079985,0.0004344331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007734898,"about_ca_system_score_gemma":0.0000804027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001948778,"about_ca_topic_score_gemma":0.00001587477,"domain_scores_codex":[0.9974082,0.0003128352,0.0007158948,0.0005274062,0.0003887889,0.0006468644],"domain_scores_gemma":[0.9988083,0.0003579686,0.00005260243,0.0005059611,0.000006467617,0.0002686851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008760475,0.0002942309,0.00001008851,0.004049459,0.0001375836,0.0002507257,0.000845818,0.0001637286,0.00002560065,0.001360641,0.01021261,0.9826407],"study_design_scores_gemma":[0.000157024,0.00001659383,0.000002718952,0.0005924267,0.00001295577,0.00008015332,0.0000461877,0.002881774,0.0001328231,0.0005568595,0.9951305,0.0003899836],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007446609,0.9945909,0.0003512813,0.00002392776,0.00106848,0.0007453327,0.0001600649,0.0002143725,0.002100929],"genre_scores_gemma":[0.002964339,0.9947895,0.0006049981,0.00003769551,0.0001153979,0.0009416973,0.0004362762,0.0001030068,0.00000713388],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9849179,"threshold_uncertainty_score":0.9998037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2187735115086107,"score_gpt":0.4240088231099489,"score_spread":0.2052353116013382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}