{"id":"W4295753984","doi":"10.1093/asj/sjac253","title":"The Efficacy and Duration of Onabotulinum Toxin A in Improving Upper Facial Expression Lines With 64-Unit Dose Optimization: A Systematic Review and Meta-Analysis With Trial Sequential Analysis of the Randomized Controlled Trials","year":2022,"lang":"en","type":"review","venue":"Aesthetic Surgery Journal","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Meta-analysis; Randomized controlled trial; Forehead; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02314375,0.002986288,0.02387906,0.005309455,0.0006461537,0.003398986,0.002240742,0.002212094,0.003401631],"category_scores_gemma":[0.03769188,0.001629505,0.05176087,0.006368071,0.0009898456,0.002083417,0.001306249,0.002142266,0.0002701604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002910856,"about_ca_system_score_gemma":0.004080401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004249636,"about_ca_topic_score_gemma":0.008001658,"domain_scores_codex":[0.9845308,0.008013793,0.004360493,0.001471062,0.001262163,0.0003616845],"domain_scores_gemma":[0.9682053,0.02402309,0.00511948,0.0008059789,0.001505919,0.0003402512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.006298252,0.00005412713,0.00252756,0.2689701,0.7105073,0.00006636944,0.00006688928,0.0005007875,0.0002163857,0.0001046165,0.0002669597,0.01042068],"study_design_scores_gemma":[0.001612476,0.0003839034,0.001662979,0.01100012,0.9842627,0.00003903892,0.00003038913,0.0001577612,0.00009089051,0.0001231242,0.0006205405,0.00001606352],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01031433,0.9869021,0.000859939,0.0002050828,0.0002197545,0.0007774713,0.0003986507,0.00002892951,0.000293756],"genre_scores_gemma":[0.2936866,0.6948884,0.005187921,0.001158218,0.0003863949,0.00326357,0.0009380642,0.00005624254,0.0004346959],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02387906,"threshold_uncertainty_score":0.1223973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09340880339374943,"score_gpt":0.3399731132927037,"score_spread":0.2465643098989543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}