{"id":"W4295759488","doi":"10.1002/cncr.34445","title":"Early‐phase clinical trial eligibility and response evaluation criteria for refractory, relapsed, or progressive neuroblastoma: A consensus statement from the National Cancer Institute Clinical Trials Planning Meeting","year":2022,"lang":"en","type":"article","venue":"Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute; National Institutes of Health; Cancer Research UK; Institute of Cancer Research; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Medicine; Clinical trial; Progressive disease; Disease; Neuroblastoma; Refractory (planetary science); Internal medicine; Oncology; Ganglioneuroblastoma; Intensive care medicine; Ganglioneuroma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.4187193,0.002867883,0.006269594,0.004907263,0.004175628,0.009076627,0.01684684,0.01587109,0.002100897],"category_scores_gemma":[0.231529,0.002266386,0.007459348,0.006687372,0.005166381,0.0045643,0.005856478,0.0284466,0.002570356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009706459,"about_ca_system_score_gemma":0.06795295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005582524,"about_ca_topic_score_gemma":0.008750069,"domain_scores_codex":[0.7062199,0.2159687,0.04284342,0.004528593,0.02527697,0.005162492],"domain_scores_gemma":[0.6393977,0.1514834,0.05246859,0.01761788,0.1159668,0.02306558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006502728,0.002029647,0.008985731,0.02101026,0.002049515,0.001348269,0.003451375,0.007234371,0.009955037,0.03130397,0.5031711,0.4029579],"study_design_scores_gemma":[0.01123062,0.003064652,0.02180179,0.03344088,0.00325774,0.002126985,0.001735999,0.009894068,0.009603392,0.03323826,0.8699465,0.0006589582],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.01481143,0.09756264,0.2181341,0.3387478,0.01704444,0.2405989,0.008893264,0.001545355,0.06266209],"genre_scores_gemma":[0.0625348,0.03405217,0.5700839,0.1112097,0.008705453,0.18517,0.0163931,0.0007499239,0.01110101],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.4187193,"threshold_uncertainty_score":0.7168226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5732905551472405,"score_gpt":0.6542825427937574,"score_spread":0.08099198764651694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}