{"id":"W4295759488","doi":"10.1002/cncr.34445","title":"Early‐phase clinical trial eligibility and response evaluation criteria for refractory, relapsed, or progressive neuroblastoma: A consensus statement from the National Cancer Institute Clinical Trials Planning Meeting","year":2022,"lang":"en","type":"article","venue":"Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute; National Institutes of Health; Cancer Research UK; Institute of Cancer Research; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Medicine; Clinical trial; Progressive disease; Disease; Neuroblastoma; Refractory (planetary science); Internal medicine; Oncology; Ganglioneuroblastoma; Intensive care medicine; Ganglioneuroma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02011426,0.0002160896,0.0007152521,0.00007609285,0.000530801,0.00007275942,0.0001354894,0.00009142346,0.0004898817],"category_scores_gemma":[0.03284133,0.0001400858,0.0002404433,0.000176018,0.0003353458,0.00009291595,0.0001646779,0.0005907935,0.000002279264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000580003,"about_ca_system_score_gemma":0.00393414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002083462,"about_ca_topic_score_gemma":0.00006566629,"domain_scores_codex":[0.9894125,0.006593567,0.001689513,0.0007911279,0.00115815,0.0003551754],"domain_scores_gemma":[0.9862577,0.01177215,0.0008209724,0.000291701,0.0005788283,0.0002786397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9275905,0.001438468,0.005059053,0.0000294503,0.0007517815,0.0001745363,0.000455639,0.00007054855,0.001536422,0.000003851925,0.02852887,0.03436082],"study_design_scores_gemma":[0.7161229,0.0383579,0.1069406,0.000629378,0.002175341,0.00005008557,0.0005699052,0.01206058,0.000723354,0.0004542856,0.1213604,0.0005552291],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836063,0.001214022,0.00001399865,0.004995308,0.002175617,0.006261707,0.001674687,0.00004021069,0.00001808917],"genre_scores_gemma":[0.9904982,0.0001434612,0.0003262846,0.00120667,0.001667061,0.005845062,0.0001163755,0.00003396583,0.0001628714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2114676,"threshold_uncertainty_score":0.9753054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5732905551472405,"score_gpt":0.6542825427937574,"score_spread":0.08099198764651694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}