{"id":"W4295828435","doi":"10.1016/j.annonc.2022.07.1429","title":"1297P Adjuvant gemcitabine is as efficient as mFOLFIRINOX in patients with GemPred+ tumor signature and resected pancreatic adenocarcinoma (PDAC): An ancillary study of the PRODIGE-24 clinical trial","year":2022,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Gemcitabine; Internal medicine; Pancreatic ductal adenocarcinoma; Adenocarcinoma; Oncology; Adjuvant; Clinical trial; Pancreatic cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001345819,0.000845481,0.001854755,0.0002372138,0.0002393929,0.001129206,0.0004269583,0.0008763971,0.002358939],"category_scores_gemma":[0.001092877,0.0003187845,0.001542093,0.0002542759,0.0005799609,0.001092664,0.0003636908,0.002420183,0.00063168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006752679,"about_ca_system_score_gemma":0.0006787155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004023116,"about_ca_topic_score_gemma":0.001337413,"domain_scores_codex":[0.9996002,0.0001916769,0.00002387814,0.00008036671,0.00003441221,0.00006946833],"domain_scores_gemma":[0.9994912,0.0001298409,0.00009296028,0.0000670401,0.00002851039,0.0001904122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7866136,0.009184116,0.01358016,0.0005066125,0.00272849,0.000220375,0.0001437772,0.002633835,0.01739538,0.0002827584,0.003290147,0.1634207],"study_design_scores_gemma":[0.4016072,0.4853102,0.08155512,0.0001728891,0.004836284,0.0009051516,0.0002280847,0.004214837,0.009981168,0.00120106,0.009847444,0.0001404932],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962088,0.001659111,0.0001322082,0.00045143,0.0001141467,0.0001171006,0.0003544104,0.00004086054,0.0009219378],"genre_scores_gemma":[0.9962382,0.0009566909,0.0002869107,0.0003296871,0.00008405486,0.00009231039,0.0008817372,0.0000149114,0.001115409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002358939,"threshold_uncertainty_score":0.007891476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03664091110392732,"score_gpt":0.3410152514717964,"score_spread":0.3043743403678691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}