{"id":"W4295836924","doi":"10.1016/j.annonc.2022.07.1612","title":"1509P Efficacy and safety of vimseltinib in tenosynovial giant cell tumour (TGCT): Phase II expansion","year":2022,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Musculoskeletal synovial abnormalities and treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001166372,0.0009513878,0.001579984,0.0003244736,0.0003032141,0.001290177,0.0007004948,0.001024342,0.00425004],"category_scores_gemma":[0.0007044852,0.0003940575,0.001585742,0.0003036078,0.0007095017,0.0009562611,0.0002942361,0.002962846,0.001154722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001064582,"about_ca_system_score_gemma":0.00124485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009262202,"about_ca_topic_score_gemma":0.002542701,"domain_scores_codex":[0.9997094,0.00008675806,0.00002027611,0.0000450444,0.00003961677,0.00009886372],"domain_scores_gemma":[0.9996936,0.00006206812,0.00005939029,0.00003052619,0.00003449054,0.0001200529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4305064,0.03768705,0.00709268,0.003363092,0.003435284,0.0004773478,0.0006745617,0.009097971,0.08969925,0.001489372,0.01582331,0.4006537],"study_design_scores_gemma":[0.4667112,0.4693713,0.0200092,0.0004278294,0.002253429,0.001164313,0.0003429907,0.004436317,0.01525439,0.001162592,0.01873671,0.0001296613],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845425,0.007365283,0.0007115068,0.0008503833,0.000217191,0.001356525,0.001541591,0.0001385348,0.003276537],"genre_scores_gemma":[0.9854197,0.004746914,0.001129316,0.001083377,0.0001060163,0.001267102,0.002376768,0.00004692562,0.003823965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00425004,"threshold_uncertainty_score":0.01421785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04119981162441962,"score_gpt":0.3602155427157212,"score_spread":0.3190157310913016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}