{"id":"W4295868801","doi":"10.2139/ssrn.4199630","title":"Highly Potent Naturally Acquired Human Monoclonal Antibodies Against Pfs48/45 Block <i>Plasmodium falciparum</i> Transmission to Mosquitoes","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; AbCellera (Canada); University of Toronto","funders":"","keywords":"Virology; Plasmodium falciparum; Monoclonal antibody; Transmission (telecommunications); Biology; Antibody; Malaria; Immunology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002935648,0.0003817868,0.0002150412,0.0001535669,0.000130597,0.0002130795,0.000309732,0.000289705,0.003695619],"category_scores_gemma":[0.0001983833,0.0001866243,0.0001775563,0.00008982835,0.0001609569,0.0001475875,0.0001735602,0.000843342,0.0008534237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003070672,"about_ca_system_score_gemma":0.0002481111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007757872,"about_ca_topic_score_gemma":0.001424305,"domain_scores_codex":[0.9998496,0.00003092689,0.000008832912,0.00002525608,0.00002504097,0.00006037122],"domain_scores_gemma":[0.9999061,0.00003062971,0.00001730868,0.00001394885,0.00001074169,0.00002131754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000302636,0.0001361195,0.0001905871,0.00005866912,0.00001611895,0.00004596111,0.00002339794,0.0001822451,0.9940175,0.0004061839,0.0006252339,0.003995422],"study_design_scores_gemma":[0.0002476669,0.001843139,0.00272832,0.00001114698,0.00004336435,0.0004936983,0.00001553843,0.001198845,0.983407,0.0001335389,0.009871621,0.000006136459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772653,0.002533855,0.008020584,0.000285155,0.0001709802,0.000176594,0.0008471409,0.0003065762,0.01039384],"genre_scores_gemma":[0.9892252,0.0009076432,0.003406629,0.0001212803,0.00004339201,0.00008973199,0.0008335792,0.00002611001,0.005346415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003695619,"threshold_uncertainty_score":0.01236302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391051516826083,"score_gpt":0.2815571254163667,"score_spread":0.2676466102481059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}