{"id":"W4295875408","doi":"10.1101/2022.09.09.507377","title":"SPECC1L binds MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Myosin; Myosin-light-chain phosphatase; Cell biology; Biology; Protein phosphatase 1; Actin; Protein subunit; Cytoskeleton; Phosphatase; Phosphorylation; Myosin light-chain kinase; Actin cytoskeleton; Microtubule; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638984,0.0003960142,0.0002885107,0.0002416907,0.0004183723,0.0002821021,0.0002920809,0.0003257056,0.002131952],"category_scores_gemma":[0.0002189701,0.0001679204,0.0003103207,0.0002108298,0.0001906549,0.0001803491,0.000357618,0.0005081252,0.0007527593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009361008,"about_ca_system_score_gemma":0.0002015707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000973951,"about_ca_topic_score_gemma":0.001379497,"domain_scores_codex":[0.999729,0.00002700175,0.00001087928,0.00008025405,0.00008221608,0.00007067099],"domain_scores_gemma":[0.9998884,0.00001152447,0.00002744121,0.00001007786,0.00002255122,0.00004004486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007361796,0.00001444399,0.000528837,0.00005019059,0.000008915945,0.00008043696,0.0000101085,0.00005816239,0.9978234,0.00008650136,0.0002144953,0.001050988],"study_design_scores_gemma":[0.00002472705,0.000102261,0.0203282,0.00001923557,0.000017059,0.0006653121,0.00004062933,0.004756674,0.9661066,0.00008340137,0.007843602,0.00001220499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848214,0.005099143,0.004846603,0.0002996167,0.00006043065,0.00004066989,0.0008301125,0.0001716496,0.003830283],"genre_scores_gemma":[0.9923444,0.0006682083,0.002038782,0.0002169129,0.00001680119,0.00005936984,0.001706639,0.00003472133,0.00291409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002131952,"threshold_uncertainty_score":0.007132053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048586781534891,"score_gpt":0.2172651374270113,"score_spread":0.2067792696116624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}