{"id":"W4295932518","doi":"10.1101/2022.09.15.508085","title":"Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium <i>Deinococcus radiodurans</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Advanced Electron Microscopy Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Lister Institute of Preventive Medicine; Leverhulme Trust; Max-Planck-Gesellschaft; UK Research and Innovation; European Molecular Biology Organization","keywords":"S-layer; Deinococcus radiodurans; Random hexamer; Biophysics; Bacteria; Crystallography; Cell envelope; Archaea; Biology; Layer (electronics); Chemistry; Materials science; Nanotechnology; Biochemistry; Genetics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003211479,0.0004262766,0.0003503118,0.00003457416,0.0003371935,0.0000763971,0.001349212,0.0002798715,0.00005063013],"category_scores_gemma":[0.00004419851,0.0003238698,0.0002860471,0.0003721686,0.0002346411,0.00001022115,0.001115645,0.000676399,0.000003323588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487673,"about_ca_system_score_gemma":0.0003763669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003812103,"about_ca_topic_score_gemma":0.000002332644,"domain_scores_codex":[0.998025,0.0001142117,0.0004727029,0.0007143641,0.0002099459,0.0004638039],"domain_scores_gemma":[0.9970804,0.0000211128,0.0004469951,0.002142659,0.000237271,0.00007156872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004482124,0.00007743319,0.000684985,0.00006588428,0.0001014331,8.347577e-7,0.000008193774,0.0003918617,0.9972141,0.00008172093,0.00132677,0.000001984401],"study_design_scores_gemma":[0.0001947854,0.00005890585,0.001915132,0.00004315849,0.000054689,7.22684e-8,0.000006821104,0.00002936849,0.8788952,0.00000663634,0.1184621,0.000333224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866185,0.002779433,0.007532912,0.0005440078,0.0003842913,0.001263706,0.0007292482,0.0001025609,0.00004531071],"genre_scores_gemma":[0.9956955,0.0008677802,0.00244455,0.0002881684,0.0001314165,0.000394226,0.000005042142,0.0001052368,0.00006812718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1183189,"threshold_uncertainty_score":0.9999213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009160240258232581,"score_gpt":0.2401573623628573,"score_spread":0.2309971221046248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}