{"id":"W4295932518","doi":"10.1101/2022.09.15.508085","title":"Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium <i>Deinococcus radiodurans</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Advanced Electron Microscopy Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Lister Institute of Preventive Medicine; Leverhulme Trust; Max-Planck-Gesellschaft; UK Research and Innovation; European Molecular Biology Organization","keywords":"S-layer; Deinococcus radiodurans; Random hexamer; Biophysics; Bacteria; Crystallography; Cell envelope; Archaea; Biology; Layer (electronics); Chemistry; Materials science; Nanotechnology; Biochemistry; Genetics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004816263,0.0001376641,0.00007261442,0.0001774298,0.0001463579,0.0002380487,0.0001752056,0.0001657068,0.0005179429],"category_scores_gemma":[0.00008414829,0.0001110058,0.0001103277,0.0001040991,0.0001678245,0.0001278714,0.0002257439,0.0001745926,0.0001919174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144346,"about_ca_system_score_gemma":0.00008658895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001156288,"about_ca_topic_score_gemma":0.001036916,"domain_scores_codex":[0.9999608,0.000003402319,0.000001990205,0.00001195797,0.00001119543,0.00001060788],"domain_scores_gemma":[0.9999369,0.000007426049,0.00002212729,0.000008076489,0.00001133909,0.00001402932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001973201,0.000003896756,0.0009941035,0.00001268517,0.000004568739,0.0001070726,0.00003326526,0.0000751949,0.9979784,0.00007482899,0.00003002959,0.0006662341],"study_design_scores_gemma":[0.00001685847,0.0001829246,0.09468098,0.00002436804,0.0000370803,0.001087106,0.0003255907,0.004667303,0.8936324,0.0002237578,0.005106108,0.0000156422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972481,0.0002334562,0.001453223,0.00002595774,0.000003794137,0.000003268415,0.00007748479,0.00003540988,0.000919274],"genre_scores_gemma":[0.9975554,0.00008886454,0.001556073,0.00002427747,0.000002782787,0.000003282867,0.0001751432,0.00001088314,0.0005832722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001156288,"threshold_uncertainty_score":0.00229907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009160240258232581,"score_gpt":0.2401573623628573,"score_spread":0.2309971221046248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}