{"id":"W4296028989","doi":"10.1210/clinem/dgac536","title":"Granulosa Cell Dysfunction Is Associated With Diminished Ovarian Response in <i>FMR1</i> Premutation Carriers","year":2022,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation","keywords":"FMR1; Endocrinology; Internal medicine; Biology; Granulosa cell; Trinucleotide repeat expansion; Follicular phase; Stimulation; Ovarian follicle; Follicle-stimulating hormone receptor; Hormone; Ovary; Follicle-stimulating hormone; Cell biology; Medicine; Luteinizing hormone; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462846,0.0003666645,0.0002404449,0.0005301607,0.0001820162,0.0002260465,0.0002192839,0.0005184698,0.002987275],"category_scores_gemma":[0.0004363533,0.000129127,0.0002094597,0.0002464569,0.0005629328,0.0001159877,0.0002504041,0.0002652348,0.0002717703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00015764,"about_ca_system_score_gemma":0.0001089485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005743661,"about_ca_topic_score_gemma":0.0003659274,"domain_scores_codex":[0.9998773,0.00001736876,0.00001632426,0.00004081981,0.00002824385,0.00001991084],"domain_scores_gemma":[0.9996564,0.00005323213,0.0001939735,0.00002533488,0.00001180538,0.00005914876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001896256,0.00007803475,0.03701485,0.0001592656,0.00005006159,0.01282935,0.0001715795,0.0001136718,0.940998,0.000269248,0.0002486686,0.006171214],"study_design_scores_gemma":[0.0001362882,0.002105609,0.5385833,0.00005850783,0.0002584838,0.1355117,0.000547946,0.001349164,0.3145324,0.000644967,0.006228418,0.0000431459],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985186,0.0003890353,0.0004008551,0.00005788794,0.00001058076,0.00001220999,0.0002237122,0.00003203199,0.0003550232],"genre_scores_gemma":[0.9988035,0.0001794533,0.0004653562,0.00003342715,0.00001080631,0.00001026685,0.000171301,0.0000144166,0.0003114477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002987275,"threshold_uncertainty_score":0.009993374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03601440308858699,"score_gpt":0.3311667896173138,"score_spread":0.2951523865287268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}