{"id":"W4296126108","doi":"10.1016/j.virusres.2022.198925","title":"More tools for our toolkit: The application of HEL-299 cells and dsRNA-nanoparticles to study human coronaviruses in vitro","year":2022,"lang":"en","type":"article","venue":"Virus Research","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada; Wilfrid Laurier University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Public Health Agency of Canada","keywords":"Biology; In vitro; Coronavirus; Virology; Inducer; Cell biology; Gene; Coronavirus disease 2019 (COVID-19); Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001326719,0.0000787387,0.0001408179,0.00003818348,0.00111382,0.0000617048,0.0003118024,0.00001966115,0.00002182463],"category_scores_gemma":[0.0001240023,0.00003237691,0.00003350917,0.000688692,0.0000803833,0.00007059151,0.0005652879,0.0001779121,0.000008558887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005703839,"about_ca_system_score_gemma":0.000007883209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00386402,"about_ca_topic_score_gemma":0.004361149,"domain_scores_codex":[0.9985885,0.0002665759,0.0002017382,0.0002716403,0.0003841667,0.0002873487],"domain_scores_gemma":[0.9991935,0.000530239,0.0000398033,0.00008914636,0.0001048617,0.00004237739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001839024,0.0003657439,0.007037854,0.000003654814,0.00001006285,6.779142e-7,0.0007637638,0.00001719106,0.9300494,0.0001833474,0.0002118077,0.06117258],"study_design_scores_gemma":[0.0003867829,0.002371859,0.4931378,0.000003769031,0.00001028231,0.000001341921,0.04594242,0.00004828258,0.4344531,0.0005366163,0.0229416,0.0001661084],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997076,0.0001063424,0.000001723998,0.0009443078,0.00001881162,0.001616352,0.0001561156,0.00001573805,0.00006461408],"genre_scores_gemma":[0.9982423,0.00001547508,0.00002621181,0.00007980155,0.00005161174,0.001499233,0.000005191054,0.000001544765,0.0000786657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4955963,"threshold_uncertainty_score":0.8566716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2060230197655328,"score_gpt":0.4176133049684125,"score_spread":0.2115902852028797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}