{"id":"W4296130467","doi":"10.1158/1557-3265.sarcomas22-a031","title":"Abstract A031: Interplay of YAP1, β-catenin and the SS18-SSX fusion protein in synovial sarcoma","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"YAP1; Gene knockdown; Biology; Luciferase; Cancer research; Fusion protein; Immunoprecipitation; Fusion gene; Catenin; Wnt signaling pathway; Transcription factor; Molecular biology; Cell biology; Cell culture; Transfection; Signal transduction; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00472584,0.00008920544,0.0002052872,0.0000854929,0.0001398407,0.00001569645,0.0003138465,0.0001337003,0.0002449537],"category_scores_gemma":[0.0004713673,0.00006994545,0.00009537747,0.0002577138,0.0006071058,0.000003733107,0.0006906391,0.0007299859,0.000002948976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007434786,"about_ca_system_score_gemma":0.0003333468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001039086,"about_ca_topic_score_gemma":0.0009349127,"domain_scores_codex":[0.9975672,0.0008453438,0.000494086,0.0003899169,0.0004328765,0.0002705885],"domain_scores_gemma":[0.9991681,0.0002130221,0.0001136578,0.0003247147,0.0001158535,0.00006465706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0178687,0.0005321131,0.02557172,0.000137521,0.0001409422,0.00001478906,0.0003503265,0.0008554222,0.8079172,0.0004925321,0.007207347,0.1389114],"study_design_scores_gemma":[0.03144242,0.005895126,0.4699426,0.0004967335,0.00006375394,0.00004376379,0.001519698,0.005019397,0.3341537,0.004919582,0.145411,0.0010923],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994591,0.002326145,0.00001132571,0.001777661,0.0001626277,0.0007038812,0.00002621528,0.000003941723,0.000397206],"genre_scores_gemma":[0.9982321,0.0005188021,0.0000253275,0.00005136434,0.0002564241,0.000311636,0.00002647941,0.00001757754,0.000560317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4737635,"threshold_uncertainty_score":0.3171466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06392768346209672,"score_gpt":0.4527018396458066,"score_spread":0.3887741561837099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}