{"id":"W4296130467","doi":"10.1158/1557-3265.sarcomas22-a031","title":"Abstract A031: Interplay of YAP1, β-catenin and the SS18-SSX fusion protein in synovial sarcoma","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"YAP1; Gene knockdown; Biology; Luciferase; Cancer research; Fusion protein; Immunoprecipitation; Fusion gene; Catenin; Wnt signaling pathway; Transcription factor; Molecular biology; Cell biology; Cell culture; Transfection; Signal transduction; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001730662,0.0002585659,0.0001979451,0.0002751256,0.0001735791,0.0002498468,0.0001318916,0.0002448626,0.001316583],"category_scores_gemma":[0.0001099875,0.0001161824,0.0002478203,0.0001979357,0.0002100651,0.0001743397,0.0001803242,0.0002901866,0.0004001149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003032364,"about_ca_system_score_gemma":0.0001840224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004774411,"about_ca_topic_score_gemma":0.0004263926,"domain_scores_codex":[0.9998935,0.00001445815,0.00001320657,0.00002560846,0.00003468753,0.00001843024],"domain_scores_gemma":[0.9999158,0.00001478997,0.00002450282,0.00000705603,0.00001211418,0.00002558511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001418088,0.00002141056,0.001361447,0.00004467445,0.000006298055,0.0001535842,0.00001192297,0.00004693863,0.9973996,0.0000356399,0.00003652724,0.0007401165],"study_design_scores_gemma":[0.00003199052,0.0006812916,0.03144718,0.000008116102,0.00003817425,0.002278342,0.0000959934,0.002093575,0.9610966,0.00008433084,0.002137835,0.000006650045],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9973296,0.001046194,0.0009430727,0.00004192669,0.000008561772,0.00001436993,0.0002156737,0.00002532023,0.0003752932],"genre_scores_gemma":[0.9974779,0.0004531154,0.0007156918,0.0000179854,0.000005018406,0.00002047182,0.000509379,0.000004601987,0.0007957566],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001316583,"threshold_uncertainty_score":0.004404366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06392768346209672,"score_gpt":0.4527018396458066,"score_spread":0.3887741561837099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}