{"id":"W4296130475","doi":"10.1158/1557-3265.sarcomas22-b013","title":"Abstract B013: STEAP1 facilitates iron transport in ewing sarcoma to support mitochondrial activity","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Gene knockdown; Mitochondrion; Cancer research; Cell biology; Extracellular; Intracellular; Biology; Transmembrane protein; Chemistry; Biochemistry; Apoptosis; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475893,0.0002654352,0.000261622,0.0001458715,0.0002395286,0.0002768343,0.0002487176,0.0004448071,0.005714671],"category_scores_gemma":[0.0001436818,0.0001180308,0.0002686452,0.0001741796,0.0002036979,0.000314115,0.0003306955,0.0007215556,0.002088182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003174404,"about_ca_system_score_gemma":0.0001601399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003290513,"about_ca_topic_score_gemma":0.0002478408,"domain_scores_codex":[0.9998962,0.00001156351,0.00001251875,0.00003101139,0.00002745524,0.00002126793],"domain_scores_gemma":[0.9999009,0.00001459524,0.00002434558,0.00001178236,0.00001606116,0.00003223014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002208409,0.00002872371,0.000250471,0.00009576308,0.000005045895,0.0001188096,0.00001313567,0.00006017268,0.9976036,0.0002393546,0.0002508439,0.001113352],"study_design_scores_gemma":[0.00007126437,0.0003209233,0.008110371,0.00002660721,0.00002482971,0.0008588083,0.00008567235,0.002150979,0.9760159,0.0002583671,0.01206678,0.00000959358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9835433,0.003705036,0.005520598,0.0006789573,0.0001909441,0.00004834006,0.002120018,0.0002089927,0.003983718],"genre_scores_gemma":[0.9893243,0.0008533099,0.001377764,0.0001336608,0.00001753249,0.00004435207,0.00212727,0.00003573723,0.006085947],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.005714671,"threshold_uncertainty_score":0.01911753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1368826254401947,"score_gpt":0.4913750992696567,"score_spread":0.354492473829462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}