{"id":"W4296131180","doi":"10.1158/1557-3265.sarcomas22-ia007","title":"Abstract IA007: B cell immunity generation in tertiary lymphoid structures, a major determinant of sarcoma immune response to immunotherapy","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Sarcoma; Immunotherapy; CD8; Immune system; Cancer immunotherapy; Cancer research; Biology; Immunology; Cancer; Medicine; Pathology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001828374,0.0001226303,0.0001816289,0.0004009152,0.0001454368,0.0002880701,0.0001032611,0.0001534668,0.002296579],"category_scores_gemma":[0.0002521737,0.00008231532,0.0001764051,0.000256541,0.0001587968,0.0001123786,0.0001791523,0.0003440588,0.0003775026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205111,"about_ca_system_score_gemma":0.0001360205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003345186,"about_ca_topic_score_gemma":0.0002854074,"domain_scores_codex":[0.9998994,0.00002117282,0.00000763542,0.0000260337,0.00002272188,0.00002305866],"domain_scores_gemma":[0.9998005,0.00003379954,0.00006770589,0.00002122713,0.0000323411,0.00004449748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001999579,0.0001276598,0.108993,0.0001073465,0.00004594829,0.0001803375,0.00007622481,0.00028229,0.8758426,0.0001340805,0.000334542,0.0118764],"study_design_scores_gemma":[0.00007518644,0.001328991,0.8778275,0.00001698918,0.00007549294,0.001390397,0.0001330099,0.001516232,0.1152255,0.0002392733,0.002165091,0.000006414802],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983809,0.0003115285,0.0003697333,0.00002204071,0.000002213659,0.0000103613,0.0003285414,0.0000207806,0.0005539597],"genre_scores_gemma":[0.9988643,0.00005408881,0.0002697731,0.00001893309,0.000004882784,0.0000114637,0.0004501162,0.000005274143,0.0003210893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002296579,"threshold_uncertainty_score":0.0076828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0796667208367007,"score_gpt":0.4202296403562986,"score_spread":0.3405629195195979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}