{"id":"W4296131450","doi":"10.1158/1557-3265.sarcomas22-a021","title":"Abstract A021: Chimeric antigen receptor armored natural killer cell immunotherapy for osteosarcoma","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chimeric antigen receptor; Immunotherapy; NK-92; Immunology; Antibody-dependent cell-mediated cytotoxicity; Cancer immunotherapy; Cancer research; Antigen; Biology; Immune system; Natural killer T cell; T cell; Antibody; Medicine; Monoclonal antibody","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002546044,0.0002701555,0.0001951009,0.0003370632,0.0001102434,0.0002753668,0.0002308597,0.0005097876,0.003548197],"category_scores_gemma":[0.00007004021,0.00007198963,0.0003372454,0.0001942691,0.0001315028,0.0002113688,0.0002076012,0.000416612,0.0009378234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002807811,"about_ca_system_score_gemma":0.0004769521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005126811,"about_ca_topic_score_gemma":0.0005445558,"domain_scores_codex":[0.9999129,0.0000119849,0.000005728021,0.00001219244,0.00003822942,0.00001899734],"domain_scores_gemma":[0.9999745,0.000002853809,0.00000491328,0.0000020783,0.000007062948,0.000008713371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002221112,0.001408484,0.001078577,0.0008929282,0.00007423756,0.0009671905,0.00006991313,0.001455006,0.7888167,0.003888136,0.009327105,0.1898006],"study_design_scores_gemma":[0.003479017,0.02504241,0.01131143,0.00022887,0.0003641021,0.009208508,0.0001095023,0.01098883,0.6769788,0.003011085,0.2592142,0.00006323527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8759744,0.05591014,0.02124482,0.00330753,0.001731984,0.0007426782,0.0008906819,0.0008455855,0.03935208],"genre_scores_gemma":[0.942437,0.01413151,0.006661365,0.0006178692,0.0002217205,0.0001967869,0.001427021,0.00005445637,0.03425223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003548197,"threshold_uncertainty_score":0.01186991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1799178042811239,"score_gpt":0.5114094580274091,"score_spread":0.3314916537462853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}