{"id":"W4296131477","doi":"10.1158/1557-3265.sarcomas22-a004","title":"Abstract A004: Radiation-induced changes to the immune microenvironment in an immunocompetent mouse model of Ewing sarcoma","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immune system; Sarcoma; Tumor microenvironment; Cancer research; Medicine; Ewing's sarcoma; Humanized mouse; Cancer; Flow cytometry; Radiation therapy; Pathology; Immunology; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004784154,0.00082594,0.0003788634,0.001208478,0.0003126689,0.0005250135,0.0004484598,0.0009829163,0.004484704],"category_scores_gemma":[0.0001584602,0.0002842609,0.0005733026,0.0003449037,0.000603226,0.0005458497,0.0002760471,0.002095954,0.0009286862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004707546,"about_ca_system_score_gemma":0.0002587815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004349161,"about_ca_topic_score_gemma":0.0005341353,"domain_scores_codex":[0.9995053,0.00006790399,0.00006681922,0.0001496576,0.0001234763,0.00008691672],"domain_scores_gemma":[0.9995552,0.00007516955,0.0001362799,0.00007597385,0.00003874396,0.000118614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004497043,0.0003055324,0.0001865671,0.0000374606,0.000005869773,0.0001027235,0.00004072262,0.0001123286,0.997297,0.0001968689,0.0001554118,0.001109853],"study_design_scores_gemma":[0.0001082173,0.002754719,0.003304134,0.00001912598,0.00002460151,0.0005130181,0.0000633667,0.001464595,0.9876079,0.0001411739,0.003987728,0.000011455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831198,0.001195672,0.007767096,0.0003897632,0.000155737,0.000267019,0.002837643,0.0005879193,0.003679438],"genre_scores_gemma":[0.9697779,0.0009281414,0.009830938,0.0002519282,0.00005270011,0.000652126,0.002878216,0.0001647798,0.01546318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004484704,"threshold_uncertainty_score":0.01500285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.271510792115201,"score_gpt":0.4774422889300698,"score_spread":0.2059314968148689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}