{"id":"W4296132100","doi":"10.1158/1557-3265.sarcomas22-ia024","title":"Abstract IA024: Identification of a “hypoxic secretome” and its role in metastasis","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Intravasation; Extravasation; Metastasis; Biology; Primary tumor; Zebrafish; In vivo; Tumor microenvironment; Cell migration; Cancer research; Angiogenesis; Cell; Cancer; Immunology; Tumor cells; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187965,0.0002631696,0.0001776917,0.000410039,0.0001431034,0.0003313889,0.0001506528,0.0002401876,0.002087271],"category_scores_gemma":[0.0001324259,0.00009757955,0.0001767847,0.0002174353,0.0001565259,0.0001562419,0.0001638441,0.0002894237,0.0006795725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003216916,"about_ca_system_score_gemma":0.000180124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008839491,"about_ca_topic_score_gemma":0.0004689859,"domain_scores_codex":[0.9999546,0.000005667499,0.000003754271,0.000009930753,0.00001301882,0.00001310579],"domain_scores_gemma":[0.9998984,0.00001311416,0.00002321367,0.000007522114,0.00002117353,0.00003642704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000104798,0.000009834001,0.0006360545,0.00001981529,0.000002484424,0.0001188419,0.000004927184,0.00002965878,0.9978188,0.00009040479,0.00008965516,0.001074748],"study_design_scores_gemma":[0.00003975918,0.0004752631,0.07187191,0.00002155642,0.00003104988,0.002037461,0.00007581797,0.002438532,0.9100623,0.0003443272,0.01259112,0.00001104894],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825321,0.004209971,0.004945233,0.0005094026,0.00008023215,0.00006939,0.002437617,0.0001006365,0.005115415],"genre_scores_gemma":[0.9778855,0.001701553,0.005496753,0.0001692024,0.0000905924,0.00005126981,0.00549422,0.0000371927,0.009073666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002087271,"threshold_uncertainty_score":0.006982625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1142057685467738,"score_gpt":0.4668150607762514,"score_spread":0.3526092922294776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}