{"id":"W4296163095","doi":"10.1186/s12931-022-02174-8","title":"Peroxisome proliferator-activated receptor gamma gene variants modify human airway and systemic responses to indoor dibutyl phthalate exposure","year":2022,"lang":"en","type":"article","venue":"Respiratory Research","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Norges Astma- og Allergiforbund; Astma- och Allergiförbundet; National Institute of Environmental Health Sciences; Norges Forskningsråd","keywords":"Dibutyl phthalate; Phthalate; Peroxisome proliferator-activated receptor; Gene; Peroxisome; Receptor; Biology; Endocrinology; Internal medicine; Immunology; Chemistry; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00334849,0.0002874769,0.0003650377,0.0002676286,0.001491717,0.0001456052,0.0007095115,0.0001046859,0.001693854],"category_scores_gemma":[0.0005824991,0.0002560939,0.00007136509,0.0009252568,0.0002842644,0.0002115774,0.001765251,0.0009885021,0.000313493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005853724,"about_ca_system_score_gemma":0.00008237749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001878743,"about_ca_topic_score_gemma":0.000006651016,"domain_scores_codex":[0.9943653,0.0017457,0.0004463605,0.0009646856,0.001466505,0.001011476],"domain_scores_gemma":[0.9981894,0.0004105192,0.00009920091,0.0007071004,0.00006780174,0.0005259372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003862597,0.000163194,0.08122025,0.00005081733,0.00002244471,0.0001122716,0.0003848495,0.000129853,0.9130542,0.00002344876,0.003544209,0.0009082491],"study_design_scores_gemma":[0.002794046,0.004319981,0.1010216,0.0001620111,0.00002034775,0.0001999404,0.001062034,0.0001200223,0.8387665,0.000111953,0.05025487,0.001166723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970455,0.0003770192,0.000002471106,0.0002448165,0.0000830244,0.001225046,0.0001005699,0.00009900327,0.0008225627],"genre_scores_gemma":[0.9967836,0.00001651981,0.00009327495,0.0002153002,0.0001437304,0.000650654,0.00001324528,0.00006969762,0.002014008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07428769,"threshold_uncertainty_score":0.9999892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05711444400146289,"score_gpt":0.3932193783420121,"score_spread":0.3361049343405492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}